2v0e: Difference between revisions

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-[[Image:2v0e.png|left|200px]]
-{{STRUCTURE_2v0e|  PDB=2v0e  |  SCENE=  }}
+==BRK domain from human CHD7==
+<StructureSection load='2v0e' size='340' side='right'caption='[[2v0e]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2v0e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V0E FirstGlance]. <br>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ckc|2ckc]], [[2v0f|2v0f]]</div></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v0e OCA], [https://pdbe.org/2v0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v0e RCSB], [https://www.ebi.ac.uk/pdbsum/2v0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v0e ProSAT]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v0/2v0e_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v0e ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+CHD7 is a member of the chromodomain helicase DNA binding domain (CHD) family of ATP-dependent chromatin remodelling enzymes. It is mutated in CHARGE syndrome, a multiple congenital anomaly condition. CHD7 is one of a subset of CHD proteins, unique to metazoans that contain the BRK domain, a protein module also found in the Brahma/BRG1 family of helicases. We describe here the NMR solution structure of the two BRK domains of CHD7. Each domain has a compact betabetaalphabeta fold. The second domain has a C-terminal extension consisting of two additional helices. The structure differs from those of other domains present in chromatin-associated proteins.
-===BRK DOMAIN FROM HUMAN CHD7===
+Solution structure of the BRK domains from CHD7.,Allen MD, Religa TL, Freund SM, Bycroft M J Mol Biol. 2007 Aug 31;371(5):1135-40. Epub 2007 Jun 9. PMID:17603073<ref>PMID:17603073</ref>
-{{ABSTRACT_PUBMED_17603073}}
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-==About this Structure==
+<div class="pdbe-citations 2v0e" style="background-color:#fffaf0;"></div>
-[[2v0e]] is a 1 chain structure of [[Chromodomain-helicase-DNA-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0E OCA].
 ==See Also==
-*[[Chromodomain-helicase-DNA-binding protein|Chromodomain-helicase-DNA-binding protein]]
+*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
+*[[Helicase 3D structures|Helicase 3D structures]]
-==Reference==
+== References ==
-<ref group="xtra">PMID:017603073</ref><references group="xtra"/>
+<references/>
-[[Category: Homo sapiens]]
+__TOC__
-[[Category: Allen, M D.]]
+</StructureSection>
-[[Category: Bycroft, M.]]
+[[Category: Human]]
-[[Category: Freund, S M.V.]]
+[[Category: Large Structures]]
-[[Category: Religa, T L.]]
+[[Category: Allen, M D]]
+[[Category: Bycroft, M]]
+[[Category: Freund, S M.V]]
+[[Category: Religa, T L]]
 [[Category: Atp-binding]]
 [[Category: Brk domain]]