Ku protein: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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<scene name='56/567269/Ku_heterodimer/3'>heterodimer</scene> | <scene name='56/567269/Ku_heterodimer/3'>heterodimer</scene> | ||
composed of a | composed of a | ||
<scene name='56/567269/Ku70_subunit/3'>Ku70 subunit</scene> | <scene name='56/567269/Ku70_subunit/3'>Ku70 subunit</scene> or '''X-ray repair cross-complementing protein 6''' | ||
and a <scene name='56/567269/Ku80_subunit/3'>Ku80 subunit</scene> | and a <scene name='56/567269/Ku80_subunit/3'>Ku80 subunit</scene> or '''X-ray repair cross-complementing protein 5''' | ||
. This contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway. The crystal structure of the human Ku heterodimer was determined both alone and | . This contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway. The crystal structure of the human Ku heterodimer was determined both alone and | ||
<scene name='56/567269/Bound_dna/3'>bound to a 55-nucleotide DNA</scene> | <scene name='56/567269/Bound_dna/3'>bound to a 55-nucleotide DNA</scene> | ||