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'''Theoretical Model'''
{{Theoretical_model}}


The entry 1KJB is a Theoretical Model titled 'THEORETICAL MODEL OF L-SELECTIN, C-TYPE LECTIN DOMAIN, RESIDUES 1-120, CELL ADHESION MOLECULE'.
==THEORETICAL MODEL OF L-SELECTIN, C-TYPE LECTIN DOMAIN, RESIDUES 1-120, CELL ADHESION MOLECULE==
<StructureSection load='1kjb' size='340' side='right'caption='[[1kjb]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KJB FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kjb FirstGlance], [https://www.ebi.ac.uk/pdbsum/1kjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kjb ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We have complemented multiple sequence alignments of the lectin domains of the selectins with an analysis of structurally invariant regions in X-ray structures of the mannose-binding protein (MBP) and E-selectin. The analysis shows that regions of structural conservation between MBP and E-selectin extend beyond regions of rigorous sequence conservation within the selectin family and suggests that reliable three-dimensional models of selectins from different species can be generated by modification of only a few backbone segments in E-selectin. A model of the L-selectin lectin domain is built and discussed with regard to observed differences in selectin specificity.


[[Category:Theoretical Model]]
A template for generation and comparison of three-dimensional selectin models.,Bajorath J, Aruffo A Biochem Biophys Res Commun. 1995 Nov 22;216(3):1018-23. PMID:7488174<ref>PMID:7488174</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 30 09:50:37 2008''
</div>
<div class="pdbe-citations 1kjb" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Theoretical Model]]
[[Category: Large Structures]]
[[Category: Aruffo, A]]
[[Category: Bajorath, J]]

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