F-actin capping protein: Difference between revisions

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<StructureSection load='3aa7' size='350' side='right' scene='' caption='F-actin capping protein α (grey) and β subunits (green) complex with ethanosulfonic acid and Ba+2 ion (PDB code [[3aa7]]) '>
<StructureSection load='3aa7' size='350' side='right' scene='50/508421/Cv/1' caption='F-actin capping protein α (cyan) and β subunits (magenta) complex with ethanosulfonic acid and Ba+2 ion (PDB code [[3aa7]]) '>


    
    
'''F-actin capping protein''' (CapZ) regulates growth of actin filaments by capping the barbed end of the growing filament thus blocking the exchange of subunits at this end. CapZ is a heterodimer with α and β subunits<ref>PMID:122660160</ref>. For more details see [[Group:MUZIC:CapZ]].
'''F-actin capping protein''' (CapZ) regulates growth of actin filaments by capping the barbed end of the growing filament thus blocking the exchange of subunits at this end. <scene name='50/508421/Cv/4'>CapZ is a heterodimer with α and β subunits</scene>. <scene name='50/508421/Cv/5'>Ba+2 ion coordination site</scene> in CapZ (PDB code [[3aa7]])<ref>PMID:20625546</ref>, water molecules are shown as red sphesres. For more details see [[Group:MUZIC:CapZ]].
</StructureSection>
</StructureSection>


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[[6f3a]], [[6f38]], [[6f1u]], [[6f1t]], [[5nw4]], [[5afu]] - pCAPZ β in dynactin dynein complex – pig – Cryo EM<br />
[[6znl]] - pCAPZ α1+β2 in dynactin complex – Cryo EM<br />
[[5adx]] - pCAPZ α1+β2 + dynactin + actin – Cryo EM<br />
[[1izn]] – cCapZ α1+β – chicken<br />
[[1izn]] – cCapZ α1+β – chicken<br />
[[3aa7]] - cCapZ α1+β (mutant)<br />
[[3aa7]] - cCapZ α1+β (mutant)<br />
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[[3aa6]] - cCapZ α1+β (mutant) + CD2-associated protein peptide<br />
[[3aa6]] - cCapZ α1+β (mutant) + CD2-associated protein peptide<br />
[[2kxp]] - cCapZ α1+β + myotrophin – NMR<BR />
[[2kxp]] - cCapZ α1+β + myotrophin – NMR<BR />
[[3aaa]] - cCapZ α1+β + myotrophin<br />
[[3aaa]], [[7dsa]] - cCapZ α1+β + myotrophin<br />
[[7ds2]], [[7ds4]], [[7ds6]], [[7ds8]] - cCAPZ α1+β + twinfilin-1<br />
[[7ds3]] - cCAPZ α1+β + twinfilin-2<br />
[[7ccc]] - cCAPZ α1+β + twinfilin-1 + ADP<br />
[[7dsb]] - cCAPZ α1+β + twinfilin-1 + myotrophin<br />
[[4akr]] - CAPZ α1+β – slime mold<br />
[[4akr]] - CAPZ α1+β – slime mold<br />


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Michal Harel, Alexander Berchansky