1f7j: Difference between revisions

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 {{Theoretical_model}}
-{{Seed}}
-[[Image:1f7j.png|left|200px]]
-<!--
+==PL.LSU/2 GROUPII INTRON==
-The line below this paragraph, containing "STRUCTURE_1f7j", creates the "Structure Box" on the page.
+<StructureSection load='1f7j' size='340' side='right'caption='[[1f7j]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F7J FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f7j FirstGlance], [https://www.ebi.ac.uk/pdbsum/1f7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f7j ProSAT]</span></td></tr>
--->
+</table>
-{{STRUCTURE_1f7j|  PDB=1f7j  |  SCENE=  }}
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+We have used chemical footprinting, kinetic dissection of reactions and comparative sequence analysis to show that in self-splicing introns belonging to subgroup IIB, the sites that bind the 5' and 3' exons are connected to one another by tertiary interactions. This unanticipated arrangement, which contrasts with the direct covalent linkage that prevails in the other major subdivision of group II (subgroup IIA), results in a unique three-dimensional architecture for the complex between the exons, their binding sites and intron domain V. A key feature of the modeled complex is the presence of several close contacts between domain V and one of the intron-exon pairings. These contacts, whose existence is supported by hydroxyl radical footprinting, provide a structural framework for the known role of domain V in catalysis and its recently demonstrated involvement in binding of the 5' exon.
-===PL.LSU/2 GROUPII INTRON===
+A three-dimensional perspective on exon binding by a group II self-splicing intron.,Costa M, Michel F, Westhof E EMBO J. 2000 Sep 15;19(18):5007-18. PMID:10990464<ref>PMID:10990464</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_10990464}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1f7j" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 10990464 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_10990464}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Theoretical Model]]
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7J OCA].
+[[Category: Large Structures]]
-==Reference==
-<ref group="xtra">PMID:10990464</ref><references group="xtra"/>
 [[Category: Costa, M]]
 [[Category: Michel, F]]
 [[Category: Westhof, E]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  8 06:44:23 2010''