1cjh: Difference between revisions

No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Theoretical_model}}
{{Theoretical_model}}
{{Seed}}
[[Image:1cjh.png|left|200px]]


<!--
==WHEY ACIDIC PROTEIN (WAP) FROM PIG (SUS SCROFA)==
The line below this paragraph, containing "STRUCTURE_1cjh", creates the "Structure Box" on the page.
<StructureSection load='1cjh' size='340' side='right'caption='[[1cjh]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CJH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cjh FirstGlance], [https://www.ebi.ac.uk/pdbsum/1cjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cjh ProSAT]</span></td></tr>
-->
</table>
{{STRUCTURE_1cjh|  PDB=1cjh  |  SCENE=  }}
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Whey acidic proteins (WAP) from the mouse, rat, rabbit, camel, and pig comprise two "four-disulfide core" domains. From a detailed analysis of all sequences containing this domain, we propose a new PROSITE motif ([KRHGVLN]-X- inverted question markPF inverted question mark-X-[CF]-[PQSVLI]-X(9,19)-C- inverted question markP inverted question mark-X-[DN]-X- inverted question markN inverted question mark -[CE]-X(5)-C-C) to accurately identify new four-disulfide core proteins. A consensus model for the WAP proteins is proposed, based on the human mucous proteinase inhibitor crystal structure. This article presents a detailed atomic model for the two-domain porcine WAP sequence by comparative modeling. Surface electrostatic potential calculations indicate that the second domain of the pig WAP model is similar to the functional human mucous proteinase inhibitor domains, whereas the first domain may be nonfunctional.


===WHEY ACIDIC PROTEIN (WAP) FROM PIG (SUS SCROFA)===
The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling.,Ranganathan S, Simpson KJ, Shaw DC, Nicholas KR J Mol Graph Model. 1999 Apr;17(2):106-13, 134-6. PMID:10680116<ref>PMID:10680116</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<!--
</div>
The line below this paragraph, {{ABSTRACT_PUBMED_10680116}}, adds the Publication Abstract to the page
<div class="pdbe-citations 1cjh" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 10680116 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_10680116}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Theoretical Model]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJH OCA].
[[Category: Large Structures]]
 
==Reference==
<ref group="xtra">PMID:10680116</ref><references group="xtra"/>
[[Category: Nicholas, K R]]
[[Category: Nicholas, K R]]
[[Category: Ranganathan, S]]
[[Category: Ranganathan, S]]
[[Category: Shaw, D C]]
[[Category: Shaw, D C]]
[[Category: Simpson, K J]]
[[Category: Simpson, K J]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  8 07:04:33 2010''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA