2pji: Difference between revisions

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-[[Image:2pji.jpg|left|200px]]
- {{Structure
+==Solution structure of rhodostomin P48A mutant==
-|PDB= 2pji |SIZE=350|CAPTION= <scene name='initialview01'>2pji</scene>
+<StructureSection load='2pji' size='340' side='right'caption='[[2pji]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2pji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agkistrodon_rhodostoma Agkistrodon rhodostoma]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1xaz 1xaz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PJI FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Agkistrodon rhodostoma])</td></tr>
-|GENE= RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pji OCA], [https://pdbe.org/2pji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pji RCSB], [https://www.ebi.ac.uk/pdbsum/2pji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pji ProSAT]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pji OCA], [http://www.ebi.ac.uk/pdbsum/2pji PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pji RCSB]</span>
+[[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pj/2pji_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pji ConSurf].
+<div style="clear:both"></div>
-'''Solution structure of rhodostomin P48A mutant'''
+==See Also==
+*[[Disintegrin|Disintegrin]]
+__TOC__
-==About this Structure==
+</StructureSection>
-PJI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. This structure supersedes the now removed PDB entry 1XAZ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJI OCA].
+[[Category: Agkistrodon rhodostoma]]
-[[Category: Calloselasma rhodostoma]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Chuang, W J]]
-[[Category: Chuang, W J.]]
+[[Category: Liu, Y C]]
-[[Category: Liu, Y C.]]
+[[Category: Shiu, J H]]
-[[Category: Shiu, J H.]]
+[[Category: Disintegrin]]
-[[Category: disintegrin]]
+[[Category: Hydrolase]]
-[[Category: rhodostomin]]
+[[Category: Rhodostomin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:36:50 2008''