2ph5: Difference between revisions

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[[Image:2ph5.png|left|200px]]


{{STRUCTURE_2ph5|  PDB=2ph5  |  SCENE=  }}
==Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54==
 
<StructureSection load='2ph5' size='340' side='right'caption='[[2ph5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ph5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legph Legph]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PH5 FirstGlance]. <br>
 
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[2ph5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA].  
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hss, lpg2495 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 LEGPH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ph5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ph5 OCA], [https://pdbe.org/2ph5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ph5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ph5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ph5 ProSAT], [https://www.topsan.org/Proteins/NESGC/2ph5 TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2ph5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ph5 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homospermidine synthase]]
[[Category: Homospermidine synthase]]
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]]
[[Category: Large Structures]]
[[Category: Acton, T B.]]
[[Category: Legph]]
[[Category: Baran, M C.]]
[[Category: Acton, T B]]
[[Category: Cunningham, K.]]
[[Category: Baran, M C]]
[[Category: Fang, Y.]]
[[Category: Cunningham, K]]
[[Category: Forouhar, F.]]
[[Category: Fang, Y]]
[[Category: Hunt, J F.]]
[[Category: Forouhar, F]]
[[Category: Hussain, M.]]
[[Category: Hunt, J F]]
[[Category: Janjua, H.]]
[[Category: Hussain, M]]
[[Category: Liu, J.]]
[[Category: Janjua, H]]
[[Category: Ma, L-C.]]
[[Category: Liu, J]]
[[Category: Montelione, G T.]]
[[Category: Ma, L C]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione, G T]]
[[Category: Owens, L.]]
[[Category: Structural genomic]]
[[Category: Seetharaman, J.]]
[[Category: Owens, L]]
[[Category: Tong, L.]]
[[Category: Seetharaman, J]]
[[Category: Xiao, R.]]
[[Category: Tong, L]]
[[Category: Xiao, R]]
[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Nesg]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]

Latest revision as of 18:24, 17 June 2021

Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54

Structural highlights

2ph5 is a 1 chain structure with sequence from Legph. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Gene:hss, lpg2495 (LEGPH)
Activity:Homospermidine synthase, with EC number 2.5.1.44
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2ph5, resolution 2.50Å

Drag the structure with the mouse to rotate

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OCA