2pc2: Difference between revisions

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-[[Image:2pc2.png|left|200px]]
-{{STRUCTURE_2pc2|  PDB=2pc2  |  SCENE=  }}
+==Lysozyme Cocrystallized with Tris-dipicolinate Eu complex==
+<StructureSection load='2pc2' size='340' side='right'caption='[[2pc2]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
-===Lysozyme Cocrystallized with Tris-dipicolinate Eu complex===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2pc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PC2 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EU:EUROPIUM+ION'>EU</scene>, <scene name='pdbligand=PDC:PYRIDINE-2,6-DICARBOXYLIC+ACID'>PDC</scene></td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-[[2pc2]] is a 1 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PC2 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pc2 OCA], [https://pdbe.org/2pc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pc2 RCSB], [https://www.ebi.ac.uk/pdbsum/2pc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pc2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pc/2pc2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pc2 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:018350532</ref><references group="xtra"/>
+__TOC__
-[[Category: Gallus gallus]]
+</StructureSection>
+[[Category: Chick]]
+[[Category: Large Structures]]
 [[Category: Lysozyme]]
-[[Category: Kahn, R.]]
+[[Category: Kahn, R]]
-[[Category: Pompidor, G.]]
+[[Category: Pompidor, G]]
-[[Category: Vicat, J.]]
+[[Category: Vicat, J]]
 [[Category: Hydrolase]]