Sandbox GGC1: Difference between revisions
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==Kinesin Motor Domain== | ==Kinesin Motor Domain== | ||
<StructureSection load='1bg2' size='340' side='right' caption='Kinesin Protein' scene=''> | <StructureSection load='1bg2' size='340' side='right' caption='Kinesin Protein' scene=''> | ||
Kinesin is an ATP-dependent motor protein responsible for the transportation of cargo. It is a heterotetramer composed of light and heavy chains. | |||
== '''Function''' == | == '''Function''' == | ||
* Moving cargo usually from the center of the cell to the | * Moving cargo usually from the center of the cell to the margins <br/> | ||
* Involved in cell replication and axonal signaling | * Involved in cell replication and axonal signaling | ||
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*Charcot Marie Tooth (CMT): Charcot Marie Tooth is one of many diseases that affect the peripheral nervous system. Individuals may suffer physical disabilities due to weakness in transmission of signals firing from the central nervous system | *Charcot Marie Tooth (CMT): Charcot Marie Tooth is one of many diseases that affect the peripheral nervous system. Individuals may suffer physical disabilities due to weakness in transmission of signals firing from the central nervous system | ||
== '''Structural highlights''' == | == '''Structural highlights''' == | ||
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
#file:///C:/Users/Muna/Desktop/Spring%202021/Advanced%20Biochem/pcbi.1003329.pdf | |||
#https://www.ncbi.nlm.nih.gov/books/NBK22572/#:~:text=Kinesins%20moving%20along%20microtubules%20usually,surfaces%20of%20some%20eukaryotic%20cells. | |||
#https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Charcot-Marie-Tooth-Disease-Fact-Sheet | |||
<references/> | <references/> | ||