2if2: Difference between revisions

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-[[Image:2if2.gif|left|200px]]<br /><applet load="2if2" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2if2, resolution 3.00&Aring;" />
-'''Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.'''<br />
-==About this Structure==
+==Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.==
-IF2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA].
+<StructureSection load='2if2' size='340' side='right'caption='[[2if2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-[[Category: Aquifex aeolicus]]
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2if2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IF2 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if2 OCA], [https://pdbe.org/2if2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2if2 RCSB], [https://www.ebi.ac.uk/pdbsum/2if2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2if2 ProSAT], [https://www.topsan.org/Proteins/NESGC/2if2 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[[https://www.uniprot.org/uniprot/COAE_AQUAE COAE_AQUAE]] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/2if2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2if2 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Aquae]]
 [[Category: Dephospho-CoA kinase]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Acton, T B.]]
+[[Category: Acton, T B]]
-[[Category: Baran, M.]]
+[[Category: Baran, M]]
-[[Category: Cunningham, K.]]
+[[Category: Cunningham, K]]
-[[Category: Fang, Y.]]
+[[Category: Fang, Y]]
-[[Category: Forouhar, F.]]
+[[Category: Forouhar, F]]
-[[Category: Hunt, J F.]]
+[[Category: Hunt, J F]]
-[[Category: Hussain, A.]]
+[[Category: Hussain, A]]
-[[Category: Hussain, M.]]
+[[Category: Hussain, M]]
-[[Category: Liu, J.]]
+[[Category: Liu, J]]
-[[Category: Ma, L C.]]
+[[Category: Ma, L C]]
-[[Category: Montelione, G T.]]
+[[Category: Montelione, G T]]
-[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Structural genomic]]
-[[Category: Rost, B.]]
+[[Category: Rost, B]]
-[[Category: Seetharaman, J.]]
+[[Category: Seetharaman, J]]
-[[Category: Tong, L.]]
+[[Category: Tong, L]]
-[[Category: Wu, M.]]
+[[Category: Wu, M]]
-[[Category: Xiao, R.]]
+[[Category: Xiao, R]]
-[[Category: EDO]]
+[[Category: Alpha-beta protein]]
-[[Category: SO4]]
+[[Category: Nesg]]
-[[Category: alpha-beta protein]]
+[[Category: PSI, Protein structure initiative]]
-[[Category: nesg]]
+[[Category: Transferase]]
-[[Category: northeast structural genomics consortium]]
-[[Category: protein structure initiative]]
-[[Category: psi-2]]
-[[Category: structural genomics]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:51:58 2008''