2if2: Difference between revisions

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[[Image:2if2.png|left|200px]]


{{STRUCTURE_2if2|  PDB=2if2  |  SCENE=  }}
==Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.==
 
<StructureSection load='2if2' size='340' side='right'caption='[[2if2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2if2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IF2 FirstGlance]. <br>
 
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[2if2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA].  
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
[[Category: Aquifex aeolicus]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if2 OCA], [https://pdbe.org/2if2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2if2 RCSB], [https://www.ebi.ac.uk/pdbsum/2if2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2if2 ProSAT], [https://www.topsan.org/Proteins/NESGC/2if2 TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/COAE_AQUAE COAE_AQUAE]] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/2if2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2if2 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aquae]]
[[Category: Dephospho-CoA kinase]]
[[Category: Dephospho-CoA kinase]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Baran, M.]]
[[Category: Acton, T B]]
[[Category: Cunningham, K.]]
[[Category: Baran, M]]
[[Category: Fang, Y.]]
[[Category: Cunningham, K]]
[[Category: Forouhar, F.]]
[[Category: Fang, Y]]
[[Category: Hunt, J F.]]
[[Category: Forouhar, F]]
[[Category: Hussain, A.]]
[[Category: Hunt, J F]]
[[Category: Hussain, M.]]
[[Category: Hussain, A]]
[[Category: Liu, J.]]
[[Category: Hussain, M]]
[[Category: Ma, L C.]]
[[Category: Liu, J]]
[[Category: Montelione, G T.]]
[[Category: Ma, L C]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione, G T]]
[[Category: Rost, B.]]
[[Category: Structural genomic]]
[[Category: Seetharaman, J.]]
[[Category: Rost, B]]
[[Category: Tong, L.]]
[[Category: Seetharaman, J]]
[[Category: Wu, M.]]
[[Category: Tong, L]]
[[Category: Xiao, R.]]
[[Category: Wu, M]]
[[Category: Xiao, R]]
[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Nesg]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]

Latest revision as of 14:14, 31 March 2021

Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.

Structural highlights

2if2 is a 3 chain structure with sequence from Aquae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Gene:coaE (AQUAE)
Activity:Dephospho-CoA kinase, with EC number 2.7.1.24
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[COAE_AQUAE] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2if2, resolution 3.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA