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[[Image:2guh.gif|left|200px]]


{{Structure
==Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1==
|PDB= 2guh |SIZE=350|CAPTION= <scene name='initialview01'>2guh</scene>, resolution 1.52&Aring;
<StructureSection load='2guh' size='340' side='right'caption='[[2guh]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2guh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhojr Rhojr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GUH FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
|GENE= rha6424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1831 Rhodococcus sp.])
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1309 AcrR], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00440 TetR_N]</span>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rha6424 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=101510 RHOJR])</td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2guh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2guh OCA], [http://www.ebi.ac.uk/pdbsum/2guh PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2guh RCSB]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2guh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2guh OCA], [https://pdbe.org/2guh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2guh RCSB], [https://www.ebi.ac.uk/pdbsum/2guh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2guh ProSAT], [https://www.topsan.org/Proteins/MCSG/2guh TOPSAN]</span></td></tr>
}}
</table>
 
== Evolutionary Conservation ==
'''Crystal Structure of the Putative TetR-family Transcriptional Regulator from Rhodococcus sp. RHA1'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2guh_consurf.spt"</scriptWhenChecked>
2GUH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUH OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Protein complex]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rhodococcus sp.]]
  </jmolCheckbox>
[[Category: Edwards, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2guh ConSurf].
[[Category: Joachimiak, A.]]
<div style="clear:both"></div>
[[Category: Kim, Y.]]
__TOC__
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</StructureSection>
[[Category: Savchenko, A.]]
[[Category: Large Structures]]
[[Category: Skarina, T.]]
[[Category: Rhojr]]
[[Category: Zheng, H.]]
[[Category: Edwards, A]]
[[Category: helix-turn-helix]]
[[Category: Joachimiak, A]]
[[Category: mcsg]]
[[Category: Kim, Y]]
[[Category: midwest center for structural genomic]]
[[Category: Structural genomic]]
[[Category: protein structure initiative]]
[[Category: Savchenko, A]]
[[Category: psi]]
[[Category: Skarina, T]]
[[Category: structural genomic]]
[[Category: Zheng, H]]
[[Category: tetr fold]]
[[Category: Helix-turn-helix]]
 
[[Category: Mcsg]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:27:41 2008''
[[Category: PSI, Protein structure initiative]]
[[Category: Tetr fold]]
[[Category: Transcription]]

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