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Ubiquitin conjugating enzyme: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
The active site of Ubc contains a cysteine residue. The <scene name='55/551219/Cv/3'>ubiquitin surface which interacts with Ubc</scene><ref>PMID:21396940</ref>.
The active site of Ubc contains a cysteine residue. The <scene name='55/551219/Cv/4'>ubiquitin surface which interacts with Ubc</scene><ref>PMID:21396940</ref>.
==[[3D structures of ubiquitin conjugating enzyme]]==
</StructureSection>
</StructureSection>


== 3D Structures of ubiquitin conjugating enzyme ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Ubiquitin conjugating enzyme
**[[1jas]] – hUbc – human  <BR />
**[[2aak]] – AtUbc – ''Arabidopsis thaliana''  <BR />
**[[2qcq]], [[1fzy]] – yUbc – yeast  <BR />
**[[1fxt]] – yUbc + ubiquitin  <BR />
**[[2e2c]] – Ubc – ''Spisula solidissima''  <BR />
**[[1q34]] – CeUbc – ''Caenorhabidis elegans''  <BR />
**[[2fo3]] – Ubc – ''Plasmodium vivax''  <BR />
**[[2h2y]] – PfUbc – ''Plasmodium falciparum''  <BR />
*Ubiquitin conjugating enzyme 1
**[[2aak]] – AtUbc <BR />
**[[3we5]] – Ubc – poplar mushroom<BR />
**[[1fzy]] – yUbc  <BR />
**[[1tte]] – yUbc  (mutant) <BR />
**[[1z3d]] – CeUbc  <BR />
*Ubiquitin conjugating enzyme 2
**[[1ayz]] – yUbc  <BR />
**[[4r62]] – yUbc + ubiquitin carboxyl extension protein 80 <BR />
**[[5aie]] – yUbc +  NOT4  <BR />
**[[1z2u]] – CeUbc  <BR />
*Ubiquitin conjugating enzyme 4
**[[1qcq]] – yUbc  <BR />
**[[5aie]] – yUbc + NOT4 RING domain  <BR />
**[[4ii2]] – fyUbc  (mutant) + E1 + ATP – fission yeast<BR />
*Ubiquitin conjugating enzyme 6
**[[4jjq]] – hUbc + ubiquitin carboxyl terminal hydrolase <BR />
*Ubiquitin conjugating enzyme 7 or Ubc L3
**[[2awf]], [[2cyx]] – hUbc  <BR />
**[[1c4z]] – hUbc + E3 HECT domain <BR />
**[[1fbv]] – hUbc + E3 Cbl + ZAP-70 peptide<BR />
**[[4jqu]] – hUbc + U7BR  <BR />
**[[3sqv]] – hUbc + secreted effector protein <BR />
**[[3sy2]] – hUbc + E3 Sopa <BR />
**[[4q5e]], [[4q5h]] – hUbc (mutant) + ubiquitin + OspG<BR />
**[[6cp2]] – hUbc (mutant) + UBB + SidC<BR />
**[[6djw]], [[6djx]] – hUbc (mutant) + ubiquitin + PARKIN<BR />
**[[5tte]], [[5udh]] – hUbc (mutant) + ubiquitin + ARIH1<BR />
**[[5hpt]] – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein<BR />
**[[2ucz]] – yUbc  <BR />
*Ubiquitin conjugating enzyme 8
**[[1y6l]], [[1wzw]], [[1wzv]] – hUbc  <BR />
**[[2kjh]] – hUbc + ubiquitin <BR />
**[[4x57]] – AtUbc + membrane-anchord ubiquitin-fold protein <BR />
*Ubiquitin conjugating enzyme 9 see [[SUMO conjugating enzyme Ubc9]]
*Ubiquitin conjugating enzyme 10 or Ubc C
**[[1i7k]] – hUbc (mutant)  <BR />
**[[4yii]] – hUbc + anaphase-promoting complex subunit 2<BR />
*Ubiquitin conjugating enzyme 12 (NEDD8 conjugating enzyme; Ubc F)
**[[2edi]] – hUbc 2 UQ-CON domain - NMR  <BR />
**[[1y8x]] – hUbc + E1 NEDD8 <BR />
**[[1tt5]] – hUbc + E1 Uba3, APPBP1 subunits  <BR />
**[[1y8x]] – hUbc + E1 NEDD8 <BR />
**[[2nvu]] – hUbc + E1 NEDD8 + NEDD8<BR />
**[[3fn1]] – hUbc + E1 NEDD8-activating enzyme <BR />
**[[3tdu]] – hUbc + cullin-1 + Dcn1-like protein <BR />
**[[4p5o]] – hUbc + cullin-1 + Dcn1-like protein + Rbx1 + NEDD8<BR />
**[[4gao]] – hUbc + Dcn1-like protein <BR />
**[[3tdi]] – hUbc + defective in cullin neddylation protein <BR />
**[[3o2u]] – yUbc <BR />
*Ubiquitin conjugating enzyme 13 or Ubc N
**[[4fh1]] – hUbc (mutant) <BR />
**[[1j74]] – hMms2  <BR />
**[[1j7d]] – hUbc/Mms2  <BR />
**[[4onl]], [[4onm]], [[4onn]] – hUbc + Mms2 (mutant) <BR />
**[[4nr3]], [[4nrg]], [[4nri]] – hUbc (mutant) + Mms2 <BR />
**[[3von]] – hUbc + Otub1 + E2 variant <BR />
**[[1jbb]] – yUbc  <BR />
**[[1jat]] – yUbc/Mms2  <BR />
*Ubiquitin conjugating enzyme 13 complexes
**[[2c2v]] – hUbc + CHIP + Uev1a  <BR />
**[[3hct]], [[3hcu]] – hUbc + TNF receptor associated factor 6  <BR />
**[[4dhi]], [[4dhz]] – hUbc + OTUB1 + ubiquitin + ubiquitin aldehyde <BR />
**[[4orh]] – hUbc/Mms2 + E3 Rnf8 <BR />
**[[3von]] – hUbc/Mms2 + OTUB1 <BR />
**[[1zgu]] – hMms2 + ubiquitin - NMR <BR />
**[[5eya]] – hUbc + ubiquitin  + TRIM25 ring domain<BR />
**[[4tkp]] – hUbc  + TRIM5 ring domain<BR />
**[[2gmi]] – hUbc/Mms2 (mutant) + ubiquitin <BR />
**[[4dhj]] – hUbc  + ubiquitin + OTUB1<BR />
**[[4whv]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF8<BR />
**[[5ait]], [[5aiu]] – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4<BR />
**[[4orh]] – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8<BR />
**[[4ip3]], [[3w31]] – hUbc + Orf169b <BR />
**[[2oxq]] – Ubc + CHIP U-box - zebrafish<BR />
**[[5ojw]] – yUbc + Mms2  <BR />
**[[4dhi]] – CeUbc + OTUB1  <BR />
*Ubiquitin conjugating enzyme 16 or Ubc W
**[[2mt6]] – hUbc - NMR <BR />
*Ubiquitin conjugating enzyme B
**[[2yb6]] – hUbc<br />
**[[2y4w]] – hUbc - NMR <BR />
**[[2ybf]] – hUbc + Rad18<br />
*Ubiquitin conjugating enzyme D1
**[[2c4p]] – hUbc D1 <BR />
**[[2yho]] – hUbc D1 + E3 Mylip <BR />
**[[5fer]] – hUbc D1 + ubiquitin carboxyl extension protein 80 + TRIM25 ring <BR />
**[[4qpl]] – hUbc D1 + E3 ubiquitin-protein ligase RNF146<BR />
**[[3ptf]] – hUbc D1 + ubiquitin<BR />
**[[4ap4]] – hUbc D1 + E3 ubiquitin-protein ligase RNF4 + ubiquitin<BR />
**[[3oj4]] – hUbc D1 + tumor necrosis factor α-induced protein 3 + ubiquitin<BR />
*Ubiquitin conjugating enzyme D2
**[[2esk]], [[2clw]], [[3l1y]], [[3tgd]] – hUbc D2 <BR />
**[[2eso]], [[2esp]], [[2esq]] – hUbc D2 (mutant)<BR />
**[[1w4u]] – hUbc D2 - NMR<BR />
**[[4ddg]], [[4ddi]] – hUbc D2 + ubiquitin<BR />
**[[5ulf]], [[3a33]] – hUbc D2 (mutant) + ubiquitin <BR />
**[[4ldt]] – hUbc D2 + Otub1 + ubiquitin <BR />
**[[5d1k]], [[5d1l]], [[5d1m]] – hUbc D2 + E3 ubiquitin-protein ligase RNF25<BR />
**[[5edv]] – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF31<BR />
**[[4a49]] – hUbc D2 + E3 ubiquitin-protein ligase CBL-B<BR />
**[[4v3k]], [[4v3l]], [[4a4b]], [[4a4c]] – hUbc D2 + ZAP peptide + E3 ubiquitin-protein ligase CBL-B<BR />
**[[3zni]] – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF38<BR />
**[[5ulh]], [[5ulk]] – hUbc D2 (mutant) + ubiquitin + E3 ubiquitin-protein ligase RNF165<BR />
**[[5mnj]] – hUbc D2 (mutant) + UBB + MDM2 + MDM4<BR />
**[[5d0k]], [[5d0m]] – hUbc D2 + UBB + RING finger protein 165<BR />
**[[4ldt]] – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde<BR />
**[[4wz3]] – hUbc D2 + E3 ubiquitin-protein ligase LubX<BR />
**[[5v2w]] – hUbc D2 (mutant) + ubiquitin + TRIM23<BR />
**[[1ur6]] – hUbc D2 + Cnot4 - NMR<BR />
**[[4auq]] – hUbc D2 (mutant) + baculoviral IAP repeat-containing protein + ubiquitin<BR />
**[[3jvz]], [[3jw0]] – hUbc D2 (mutant) + E3 NEDD4-2 + ubiquitin<BR />
**[[3eb6]] – fUbc D2 + baculoviral IAP repeat-containing protein- frog<BR />
*Ubiquitin conjugating enzyme D3
**[[5egg]], [[1x23]] – hUbc D3  <BR />
**[[5ifr]] – hUbc D3 + ubiquitin  <BR />
**[[2fuh]] – hUbc D3 + ubiquitin - NMR<BR />
**[[3ugb]] – hUbc D3 (mutant) + ubiquitin<BR />
**[[3l1z]] – hUbc D3 + ubiquitin conjugating factor<BR />
**[[4s3o]], [[3rpg]] – hUbc D3 + polycomb group ring finger protein + E3 ubiquitin-protein ligase RING2<BR />
**[[4bvu]] – hUbc D3 + OspG + ubiquitin <BR />
*Ubiquitin conjugating enzyme E1
**[[3bzh]] – hUbc  <BR />
*Ubiquitin conjugating enzyme G2
**[[2cyx]] – hUbc<BR />
**[[2kly]] – hUbc - NMR<BR />
**[[3fsh]] – hUbc + autocrine motility factor receptor <BR />
**[[2lxp]] – hUbc + AMFR peptide - NMR<BR />
**[[3h8k]], [[4lad]] – hUbc + AMFR peptide <BR />
*Ubiquitin conjugating enzyme H
**[[2z5d]] – hUbc  <BR />
*Ubiquitin conjugating enzyme J2
**[[2f4w]] – hUbc  <BR />
*Ubiquitin conjugating enzyme K
**[[5dfl]] – hUbc + ubiquitin <BR />
*Ubiquitin conjugating enzyme Q1
**[[2qgx]] – hUbc  <BR />
*Ubiquitin conjugating enzyme R1
**[[3rz3]] – hUbc + inhibitor <BR />
**[[4mdk]] – hUbc + ubiquitin + inhibitor <BR />
*Ubiquitin conjugating enzyme S
**[[1zdn]] – hUbc  <BR />
**[[5bnb]] – hUbc + ubiquitin <BR />
*Ubiquitin conjugating enzyme T
**[[4ccg]] – hUbc  + E3 ubiquitin-protein ligase Fancl<BR />
*Ubiquitin conjugating enzyme Uev-1
**[[2a4d]] – hUbc catalytic domain <BR />
**[[2hlw]] – hUbc catalytic domain - NMR<BR />
**[[3e95]] – PfUbc + ubiquitin carrier protein <BR />
*Ubiquitin conjugating enzyme Z
**[[5a4p]] – hUbc <BR />
*Ubiquitin conjugating enzyme E2-25KDa (Huntington interacting protein 2 HIP-2)
**[[1yla]], [[2bep]] – hHIP-2  <BR />
**[[3e46]] – hHIP-2 (mutant)  <BR />
**[[2bf8]] – hHIP-2 + SUMO  <BR />
**[[2o25]] – hHIP-2 + Ubc9  <BR />
**[[3f92]] – hHIP-2/azorectase (mutant)  <BR />
**[[3k9o]], [[3k9p]] – hHIP-2 + ubiquitin  <BR />
}}
==References==
==References==
<references />
<references />
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, David A Taves
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