Nuclear receptor: Difference between revisions
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</ref> | </ref> | ||
SEE [[Nuclear receptors]] | |||
<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''> | <StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''> | ||
The structure of the LBD is strongly conserved throughout the familly of nuclear receptors. | The structure of the LBD is strongly conserved throughout the familly of nuclear receptors. | ||
It is a globular domain | It is a globular domain, mainly alpha | ||
<scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene> | <scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene> | ||
composed of | |||
<scene name='Nuclear_receptor/Nr-lbd-alpha/1'>12 alpha-helices</scene> | |||
arranged in a three layered sandwich, and a <scene name='Nuclear_receptor/Nr-lbd-beta/1'>beta-sheet</scene>. | |||
</StructureSection> | |||
<references/> | <references/> | ||