Vpu protein: Difference between revisions
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<StructureSection load=' | <StructureSection load='' size='340' side='right' caption='HIV-1 Vpu protein (dark olive) complex with adapter-related protein complex 1 subunits γ-1 (gold), σ-1a (khaki), μ-1 (olive green), β-1 (green) (PDB code [[4p6z]])' scene='75/750240/Cv/2'> | ||
== Function == | == Function == | ||
'''Vpu protein''' (Vpu) or '''viral protein U''' is a viroporin encoded by HIV-1<ref>PMID:26247957</ref>. Vpu is a multifunctional enhancer of viral particle release<ref>PMID:12941395</ref>. | '''Vpu protein''' (Vpu) or '''viral protein U''' is a viroporin encoded by HIV-1<ref>PMID:26247957</ref>. Vpu is a multifunctional enhancer of viral particle release<ref>PMID:12941395</ref>. <scene name='75/750240/Cv/3'>HIV-1 Vpu protein complex with adapter-related protein complex 1 subunits γ-1, σ-1a, μ-1, β-1</scene> (PDB code [[4p6z]]). | ||
For details see [[HIV and accessory proteins]]. | For details see [[HIV and accessory proteins]]. | ||
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[[2n28]] – Vpu - HIV-1 - NMR<br /> | [[2n28]] – Vpu - HIV-1 - NMR<br /> | ||
[[ | [[1pi7]], [[1pi8]], [[1pje]], [[2gof]], [[2goh]], [[2jpx]] – Vpu trans-membrane domain - NMR<br /> | ||
[[ | [[1vpu]], [[2n28]], [[2n29]], [[2k7y]] – Vpu cytoplasmic domain - NMR<br /> | ||
[[1vpu]], [[2n29]], [[2k7y]] – Vpu cytoplasmic domain - NMR<br /> | |||
[[4p6z]] – Vpu cytoplasmic domain + BST2 + AP-1 core<br /> | [[4p6z]] – Vpu cytoplasmic domain + BST2 + AP-1 core<br /> | ||
Latest revision as of 13:18, 25 January 2021
FunctionVpu protein (Vpu) or viral protein U is a viroporin encoded by HIV-1[1]. Vpu is a multifunctional enhancer of viral particle release[2]. (PDB code 4p6z). For details see HIV and accessory proteins.
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3D Structures of Vpu protein3D Structures of Vpu protein
Updated on 25-January-2021
2n28 – Vpu - HIV-1 - NMR
1pi7, 1pi8, 1pje, 2gof, 2goh, 2jpx – Vpu trans-membrane domain - NMR
1vpu, 2n28, 2n29, 2k7y – Vpu cytoplasmic domain - NMR
4p6z – Vpu cytoplasmic domain + BST2 + AP-1 core
ReferencesReferences
- ↑ Gonzalez ME. Vpu Protein: The Viroporin Encoded by HIV-1. Viruses. 2015 Aug 4;7(8):4352-68. doi: 10.3390/v7082824. PMID:26247957 doi:http://dx.doi.org/10.3390/v7082824
- ↑ Bour S, Strebel K. The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes Infect. 2003 Sep;5(11):1029-39. PMID:12941395