Transposase: Difference between revisions
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<StructureSection load='3ecp' size='350' side='right' caption='Structure of Tn5 transposase complex with DNA and glycerol (PDB code [[3ecp]]).' scene=''> | <StructureSection load='3ecp' size='350' side='right' caption='Structure of Tn5 transposase complex with DNA and glycerol (PDB code [[3ecp]]).' scene='59/596996/Cv/8'> | ||
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
Transposase contains a <scene name='59/596996/Cv/ | <scene name='59/596996/Cv/9'>The Biological Assembly of Tn5 transposase is homodimer</scene> (PDB code [[3ecp]]). Transposase contains a <scene name='59/596996/Cv/7'>DDE motif in its active site</scene><ref>PMID:18790806</ref> enabling it to coordinate the binding of divalent metal ions. The metal ions affect transposase reactivity. The DDE motif is conserved in transposases and retroviral integrases and is essential for their activity. | ||
==3D structures of transposase== | ==3D structures of transposase== | ||
[[Transposase 3D structures]] | [[Transposase 3D structures]] | ||