Tryptophan RNA-binding attenuation protein: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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-<StructureSection load='2exs' size='340' side='right' caption='Structure of tryptophan RNA-binding attenuation protein complex with Trp (PDB code [[2exs]]).' scene=''>
+<StructureSection load='2exs' size='350' side='right' caption='Structure of tryptophan RNA-binding attenuation protein complex with Trp (PDB code [[2exs]]).' scene=''>
 == Function ==
-'''Tryptophan RNA-binding attenuation protein''' (TRAP) is a tryptophan-activated RNA-binding protein which regulates the expression of the tryptophan biosynthesis genes.  Down regulation of Trp biosynthesis is observed upon binding of 11 Trp to TRAP<ref>PMID:14687568</ref>.
+'''Tryptophan RNA-binding attenuation protein''' (TRAP) or '''transcription attenuation protein MtrB''' is a tryptophan-activated RNA-binding protein which regulates the expression of the tryptophan biosynthesis genes.  Down regulation of Trp biosynthesis is observed upon binding of 11 tryptophan molecules to TRAP<ref>PMID:14687568</ref>.
 == Structural highlights ==
-TRAP is composed of 11 identical subunits arranged in a symmetrical ring.  Tryptophan is bound to TRAP by mostly non-polar residues<ref>PMID:16698553</ref>.
+TRAP is composed of 11 identical subunits arranged in a <scene name='59/595823/Cv/4'>symmetrical ring</scene>. The <scene name='59/595823/Cv/3'>active site of TRAP</scene><ref>PMID:16698553</ref>. Water molecules are shown as red spheres.
 </StructureSection>
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 *Tryptophan RNA-binding attenuation protein ternary complex with Trp
-**[[1c9s]], [[1gtf]], [[1gtn]], [[1utd]], [[1utf]], [[1utv]], [[4v4f]] – GsTRAP + RNA + Trp <br />
+**[[1c9s]], [[1gtf]], [[1gtn]], [[1utd]], [[4v4f]] – GsTRAP + RNA + Trp <br />
 **[[2zp8]], [[2zp9]] – GsTRAP + TRAP inhibitory protein + Trp <br />