Oligopeptide-binding protein: Difference between revisions

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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-{{STRUCTURE_1olc|  PDB=1olc  | SIZE=400| SCENE= |right|CAPTION=Oligopeptide-binding protein (grey) complex with tetrapeptide (green)  and UO2+2 ion [[1olc]] }}
+<StructureSection load='' size='350' side='right' caption='Oligopeptide-binding protein (grey) complex with peptide bradykinin (cyan) and Cl- ion (green) (PDB entry [[3drg]])' scene='48/488461/Cv/1'>
+== Function ==
 '''Oligopeptide-binding protein''' (Opp) is a component of the
 oligopeptide permease which is an ABC-type transporter system.  Opp binds polypeptides up to pentapeptide in length with high affinity.  Opp is required for sporulation and competence.  Opp carries oligopeptides to the membrane-associated oligopeptide permease<ref>PMID:14618258</ref>.
+== Structural highlights ==
+The bradykinin peptide is nestled between the 2 domains of Opp<ref>PMID:19300437</ref>. <scene name='48/488461/Cv/6'>Bradykinin peptide binding site</scene>.
+*<scene name='48/488461/Cv/7'>Cl coordination site</scene>. Water molecule is shown as red sphere.
+</StructureSection>
 ==3D structures of oligopeptide-binding protein==
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+See [[ABC transporter]]
-{{#tree:id=OrganizedByTopic|openlevels=0|
-*Oligopeptide-binding protein
-**[[1rkm]] – StOpp – ''Salmonella typhimurium''<br />
-**[[3fto]] - LlOpp – ''Lactococcus lactis''<br />
-**[[2wol]] - ScOpp – ''Streptomyces clavuligerus''<br />
-*Oligopeptide-binding protein complex with polypeptide
-**[[1ola]], [[1olc]] – StOpp + tetrapeptide<br />
-**[[2olb]], [[1jet]], [[1jeu]], [[1jev]], [[1b1h]], [[1b3f]], [[1b3g]], [[1b3l]], [[1b32]], [[1b40]], [[1b46]], [[1b4z]], [[1b5i]], [[1b5j]], [[1b51]], [[1b52]], [[1b58]], [[1b9j]], [[1b0h]], [[1b05]], [[1qka]], [[1qkb]] - StOpp + tripeptide<br />
-**[[2rkm]] - StOpp + dipeptide<br />
-**[[1b4h]] - StOpp + Lys-DAB-Lys<br />
-**[[1b5h]] - StOpp + Lys-DPP-Lys<br />
-**[[1b6h]] - StOpp + Lys-NVA-Lys<br />
-**[[1b7h]] - StOpp + Lys-NLE-Lys<br />
-**[[1b2h]] - StOpp + Lys-ORN-Lys<br />
-**[[1b1h]] - StOpp + Lys-HPE-Lys<br />
-**[[1b3h]] - StOBpp+ Lys-ALC-Lys<br />
-**[[2z23]] - Opp + tripeptide – ''Yersinia pestis''<br />
-**[[3drf]], [[3dri]] - LlOpp + octapeptide<br />
-**[[3rya]], [[3ryb]] - LlOpp + nonapeptide<br />
-**[[3drg]] - LlOpp + bradykinin peptide<br />
-**[[3drh]] - LlOpp + hexapeptide<br />
-**[[3drj]] - LlOpp + PTH-related peptide<br />
-**[[3drk]] - LlOpp + neuropeptide S<br />
-**[[2wok]] - ScOpp + bradykinin peptide <br />
-**[[2wop]] - ScOpp + arginine<br />
-}}
 == References ==
 <references/>
 [[Category:Topic Page]]