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| {{STRUCTURE_1olc| PDB=1olc | SIZE=400| SCENE= |right|CAPTION=Oligopeptide-binding protein complex with tetrapeptide and UO2 ion [[1olc]] }}
| | <StructureSection load='' size='350' side='right' caption='Oligopeptide-binding protein (grey) complex with peptide bradykinin (cyan) and Cl- ion (green) (PDB entry [[3drg]])' scene='48/488461/Cv/1'> |
| | == Function == |
| | '''Oligopeptide-binding protein''' (Opp) is a component of the |
| | oligopeptide permease which is an ABC-type transporter system. Opp binds polypeptides up to pentapeptide in length with high affinity. Opp is required for sporulation and competence. Opp carries oligopeptides to the membrane-associated oligopeptide permease<ref>PMID:14618258</ref>. |
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| <!--
| | == Structural highlights == |
| Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page.
| | The bradykinin peptide is nestled between the 2 domains of Opp<ref>PMID:19300437</ref>. <scene name='48/488461/Cv/6'>Bradykinin peptide binding site</scene>. |
| Or use the four-green-boxes-button to insert scrollable text adjacent
| | *<scene name='48/488461/Cv/7'>Cl coordination site</scene>. Water molecule is shown as red sphere. |
| to a Jmol applet. Check out the other buttons as well!
| | </StructureSection> |
| -->
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| '''Oligopeptide-binding protein''' (OBP) is a component of the | |
| oligopeptide permease which is an ABC-type transporter system. OBP binds polypeptides up to pentapeptide in length with high affinity. OBP is required for sporulation and competence. OBP carries oligopeptides to the membrane-associated oligopeptide permease.
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| ==3D structures of oligopeptide-binding protein== | | ==3D structures of oligopeptide-binding protein== |
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| | See [[ABC transporter]] |
| [[1rkm]] – StOBP – ''Salmonella typhimurium''<br /> | |
| [[3fto]] - LlOBP – ''Lactococcus lactis''
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| '''Oligopeptide-binding protein complex with polypeptide'''
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| [[1ola]], [[1olc]] – StOBP + tetrapeptide<br />
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| [[2olb]], [[1jet]], [[1jeu]], [[1jev]], [[1b1h]], [[1b3f]], [[1b3g]], [[1b3l]], [[1b32]], [[1b40]], [[1b46]], [[1b4z]], [[1b5i]], [[1b5j]], [[1b51]], [[1b52]], [[1b58]], [[1b9j]], [[1b0h]], [[1b05]], [[1qka]], [[1qkb]] - StOBP + tripeptide<br />
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| [[2rkm]] - StOBP + dipeptide<br />
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| [[1b4h]] - StOBP + Lys-DAB-Lys<br />
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| [[1b5h]] - StOBP + Lys-DPP-Lys<br />
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| [[1b6h]] - StOBP + Lys-NVA-Lys<br />
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| [[1b7h]] - StOBP + Lys-NLE-Lys<br />
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| [[1b2h]] - StOBP + Lys-ORN-Lys<br />
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| [[1b1h]] - StOBP + Lys-HPE-Lys<br />
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| [[1b3h]] - StOBP + Lys-ALC-Lys<br />
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| [[2z23]] - OBP + tripeptide – ''Yersinia pestis''<br />
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| [[3drf]], [[3dri]] - LlOBP + octapeptide<br />
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| [[3rya]], [[3ryb]] - LlOBP + nonapeptide<br />
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| [[3drg]] - LlOBP + bradykinin<br />
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| [[3drh]] - LlOBP + hexapeptide<br />
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| [[3drj]] - LlOBP + PTH-related peptide<br />
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| [[3drk]] - LlOBP + neuropeptide S
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| | == References == |
| | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |