Sulfhydryl oxidase: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Shai Biran, Alexander Berchansky

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-{{STRUCTURE_3p0k|  PDB=3p0k  | SIZE=400| SCENE= |right|CAPTION=Baculovirus sulfhydryl oxidase complex with acetate and imidazole, showing the FAD, [[3p0k]] }}
+<StructureSection load='3p0k' size='350' side='right' scene='' caption='Baculovirus sulfhydryl oxidase complex with acetate and imidazole, showing the FAD, [[3p0k]]'>
-'''Sulfhydryl oxidase''' (SOX) is a flavin-dependent enzyme which catalyze the formation of disulfide bonds from thiol groups.  The reaction involves the reduction of O2 to hydrogen peroxide.  Erv1p SOX is involved in the biogenesis of Fe/S clusters.  ALR is a SOX augmenter of liver regeneration.  QSOX is a quiescin SOX.  QSOX contain thioredoxin domain, helix-rich domain and FAD-binding domain Erv/ALR.
-{{TOC limit|limit=2}}
+'''Sulfhydryl oxidase''' (SOX) is a flavin-dependent enzyme which catalyzes the formation of disulfide bonds from thiol groups.  The reaction involves the reduction of O<sub>2</sub> to hydrogen peroxide<ref>PMID:12176051</ref>.
-==3D structures of sulfhydryl oxidase==
+*'''Erv1p''' is involved in the biogenesis of Fe/S clusters<ref>PMID:10899311</ref>.<br />
+*'''ALR''' is a SOX augmenter of liver regeneration<ref>PMID:23186364</ref>.<br />
+*'''QSOX''' is a quiescin SOX.  QSOX contains thioredoxin domain, helix-rich domain and FAD-binding domain Erv/ALR<ref>PMID:18393449</ref>.
-''Update February 2013''
+*<scene name='46/468158/Cv/3'>FAD binding site</scene> in Baculovirus sulfhydryl oxidase ([[3p0k]]). Water molecules are shown as red spheres.
-===Erv2p===
+==3D structures of sulfhydryl oxidase==
+[[Sulfhydryl oxidase 3D structures]]
-[[1jr8]], [[1jra]] – ySOX  protease-resistant domain – yeast
-===Erv1===
-[[4e0h]] – ySOX FAD-binding domain<br />
-[[4e0i]] – ySOX FAD-binding domain (mutant)
-===Erv1p===
-[[2hj3]] – SOX – ''Arabidopsis thaliana''
-===Erv===
-[[3p0k]], [[3qzy]] – SOX – Autographa californica nucleopolyhedrovirus
-===ASFV===
-[[3gwl]] – SOX residues 1-103 – African swine fever virus
-===QSOX1===
-[[3lli]], [[3llk]] – hSOX-1 residues 286-546 – human<br />
-[[3q6o]] - hSOX-1 residues 33-272<br />
-[[3t58]], [[3t59]] - mSOX-1 residues 36-550 (mutant) - mouse
-===ALR===
-[[3mbg]], [[3tk0]] – hALR residues 81-205<br />
-[[3u2l]], [[3u2m]], [[3u5s]] – hALR (mutant)<br />
-[[3r7c]] - ALR - rat
-===FAD-linked SOX===
-[[3td7]] – SOX (mutant) – Acanthamoeba polyphaga minivirus
+</StructureSection>
+== References ==
+<references/>
 [[Category:Topic Page]]