Molecular Playground/Taxol: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Rohan Patil, Lynmarie K Thompson, Sarah Wilson, Elizabeth Cummings, Michal Harel, Alexander Berchansky

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 <StructureSection load='' size='350' side='right' caption='Paclitaxel (also known as Taxol)' scene='Rohan_Patil/Sandbox1/Taxol/6'>
-<applet size=350 frame='true' align='right'
-caption='Paclitaxel (also known as Taxol)' /> <scene name='Rohan_Patil/Sandbox1/Taxol/6'>Paclitaxel</scene>
 [[Image:Paclitaxel.png|frame|Paclitaxel (Taxol, Bristol-Myers Squibb)]]
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 Molecular Playground Banner: "Paclitaxel (Taxol),a plant-derived natural product to treat cancer"
-<Structure load='1JFF' size = '350' frame = 'true' align = 'left' caption = 'Paclitaxel binding to alpha-beta tubulin (PDB code [[1jff]])' scene='60/609785/Tubulin/2' />
+<scene name='60/609785/Tubulin/2'>Paclitaxel binding to alpha-beta tubulin</scene> (PDB code [[1jff]]).
 ==Production==
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 ==Docetaxel==
-<applet size=350 frame='true' align='left'
+*<scene name='Molecular_Playground/Taxol/Docetaxel/4'>Docetaxel (also known as Taxotere)</scene>.
-caption='Docetaxel(also known as Taxotere)' /> <scene name='Molecular_Playground/Taxol/Docetaxel/4'>Docetaxel</scene>
 Docetaxel (Taxotere, sanofi-aventis) is a semi-synthetic analog of Taxol that was discovered during the search for a more easily produced taxane anti-cancer agent. The hydroxyl group modification on docetaxel leads to an increase in the lipid solubility of the drug. It was first approved by the FDA in 1996 and is currently used in the treatment of breast, stomach and prostate cancer. Currently, Taxotere is produced from paclitaxel precursors which are extracted from ''Taxus brevifolia'', the readily available Wester Yew.