6f7g: Difference between revisions

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-'''Unreleased structure'''
-The entry 6f7g is ON HOLD
+==Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine==
+<StructureSection load='6f7g' size='340' side='right'caption='[[6f7g]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
-Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6f7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F7G FirstGlance]. <br>
-Description: Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CVW:2-(5-methyl-1~{H}-indol-3-yl)ethanamine'>CVW</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpR, rtrY, b4393, JW4356 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7g OCA], [http://pdbe.org/6f7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f7g RCSB], [http://www.ebi.ac.uk/pdbsum/6f7g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7g ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
+__TOC__
+</StructureSection>
+[[Category: Bacillus coli migula 1895]]
+[[Category: Large Structures]]
 [[Category: Hocker, B]]
 [[Category: Shanmugaratnam, S]]
-[[Category: Stiel, A.C]]
+[[Category: Stiel, A C]]
+[[Category: Ligand binding]]
+[[Category: Transcription]]