6isn: Difference between revisions
New page: '''Unreleased structure''' The entry 6isn is ON HOLD Authors: Jiang, L.L., Zhou, L., Huang, K. Description: Phosphoglycerate mutase 1 complexed with a small molecule inhibitor [[Catego... |
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==Phosphoglycerate mutase 1 complexed with a small molecule inhibitor== | |||
<StructureSection load='6isn' size='340' side='right'caption='[[6isn]], [[Resolution|resolution]] 1.98Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6isn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ISN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ISN FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AW6:4-chloro-N-(3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl)benzene-1-sulfonamide'>AW6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6isn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6isn OCA], [http://pdbe.org/6isn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6isn RCSB], [http://www.ebi.ac.uk/pdbsum/6isn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6isn ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Huang, K]] | [[Category: Huang, K]] | ||
[[Category: Jiang, L | [[Category: Jiang, L L]] | ||
[[Category: Zhou, L]] | [[Category: Zhou, L]] | ||
[[Category: Isomerase]] | |||
[[Category: Phosphoglycerate mutase 1]] | |||