Gp41: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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+<StructureSection load='1aik' size='340' side='right' caption='Core structure of acetylated gp41 from the HIV envelope glycoprotein, [[1aik]].' scene=''>
-<StructureSection load='1aik' size='340' side='right' caption='Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]].' scene=''>
 == Function ==
-'''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>.  Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120.  For more details see [[Hiv env proteins]].
+'''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>.  Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120.  For more details see [[Hiv env proteins|HIV-1 viral envelope proteins]].
 == Relevance ==
 Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell<ref>PMID:15180542</ref>.
-</StructureSection>
 == 3D Structures of Gp41 ==
+[[Gp41 3D Structures]]
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+</StructureSection>
-{{#tree:id=OrganizedByTopic|openlevels=0|
-*Gp41 from HIV-1
-**[[1aik]] – Gp41 <br />
-**[[1env]], [[3k9a]] – Gp41 (mutant)<br />
-**[[1szt]] – Gp41 thermostable domain<br />
-**[[3cp1]], [[3cyo]] – Gp41 thermostable domain (mutant)<br />
-**[[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 core<br />
-**[[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]] – Gp41 core (mutant)<br />
-**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]]  – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
-**[[2zfc]] – Gp41 N-peptide <br />
-**[[4i2l]] – Gp41 N-peptide (mutant)<br />
-**[[3u91]] – Gp41 N-terminal <br />
-**[[4hlr]] – Gp41 N-terminal (mutant) <br />
-**[[3o3x]] – arGp41 - artificial<br />
-**[[4dzu]] – arGp41 + 3-α<br />
-**[[4dzv]] – arGp41 + 4-α/β<br />
-*Gp41 from Simian Immunodeficiency Virus
-**[[2siv]] – Gp41 core<br />
-**[[2ezo]], [[2ezp]], [[2ezq]], [[2ezr]], [[2ezs]], [[1qce]] – Gp41 core - NMR<br />
-**[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br />
-}}
 == References ==
 <references/>
 [[Category:Topic Page]]