6hae: Difference between revisions
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==Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B)== | |||
<StructureSection load='6hae' size='340' side='right'caption='[[6hae]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6hae]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HAE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HAE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=E4M:1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol'>E4M</scene>, <scene name='pdbligand=FE9:IRON-GUANYLYL+PYRIDINOL+COFACTOR'>FE9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |||
[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5,10-methenyltetrahydromethanopterin_hydrogenase 5,10-methenyltetrahydromethanopterin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.98.2 1.12.98.2] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hae OCA], [http://pdbe.org/6hae PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hae RCSB], [http://www.ebi.ac.uk/pdbsum/6hae PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hae ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/A6UVT1_META3 A6UVT1_META3]] Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.[HAMAP-Rule:MF_01090] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: 5,10-methenyltetrahydromethanopterin hydrogenase]] | |||
[[Category: Large Structures]] | |||
[[Category: Ataka, K]] | [[Category: Ataka, K]] | ||
[[Category: Bill, E]] | |||
[[Category: Ermler, U]] | [[Category: Ermler, U]] | ||
[[Category: Hu, X]] | [[Category: Hu, X]] | ||
[[Category: Huang, G]] | [[Category: Huang, G]] | ||
[[Category: Shima, S]] | |||
[[Category: Wagner, T]] | |||
[[Category: Wodrich, M D]] | |||
[[Category: C1-metabolism]] | |||
[[Category: Catalytic cycle]] | |||
[[Category: Conformational rearrangement]] | |||
[[Category: Fe-guanylylpyridinol cofactor]] | |||
[[Category: Hydride-transfer]] | |||
[[Category: Methanogenesis]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Tetrahydromethanopterin]] |