6h6t: Difference between revisions
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New page: '''Unreleased structure''' The entry 6h6t is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (propandiol condition, coordination number 8)== | |||
<StructureSection load='6h6t' size='340' side='right'caption='[[6h6t]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6h6t]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H6T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H6T FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h6t OCA], [http://pdbe.org/6h6t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h6t RCSB], [http://www.ebi.ac.uk/pdbsum/6h6t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h6t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ferroxidase]] | |||
[[Category: Large Structures]] | |||
[[Category: Beck, T]] | |||
[[Category: Kuenzle, M]] | |||
[[Category: Lach, M]] | |||
[[Category: Binary nanoparticle superlattice]] | |||
[[Category: Binary protein structure]] | |||
[[Category: Charged protein container]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Protein design]] | |||
[[Category: Protein engineering]] | |||
[[Category: Self-assembly]] | |||
Latest revision as of 19:28, 14 August 2019
Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (propandiol condition, coordination number 8)Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (propandiol condition, coordination number 8)
Structural highlights
Function[FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). |
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