Polyamine oxidase: Difference between revisions
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'''Polyamine oxidase''' (PAO) catalyzes the conversion of N-acetylspermine, molecular oxygen and water to N-acetylspermidine, 3-aminopropanol and hydrogen peroxide. PAO via its production of hydrogen peroxide, is one of the key elements for oxidative burst which induces programmed cell death. PAO is involved in polyamine catabolism and uses FAD as a cofactor<ref>PMID:8584670</ref>. | '''Polyamine oxidase''' (PAO) catalyzes the conversion of N-acetylspermine, molecular oxygen and water to N-acetylspermidine, 3-aminopropanol and hydrogen peroxide. PAO via its production of hydrogen peroxide, is one of the key elements for oxidative burst which induces programmed cell death. PAO is involved in polyamine catabolism and uses FAD as a cofactor<ref>PMID:8584670</ref>. | ||
*<scene name='48/486448/Cv/ | *<scene name='48/486448/Cv/7'>FAD binding site</scene>. Water molecules are shown as red spheres. | ||
*<scene name='48/486448/Cv/5'>Spermidine binding site</scene>. | *<scene name='48/486448/Cv/5'>Spermidine binding site</scene>. | ||
*<scene name='48/486448/Cv/6'>Whole active site</scene>. | *<scene name='48/486448/Cv/6'>Whole active site</scene>. | ||