Neurophysin: Difference between revisions
Michal Harel (talk | contribs) New page: <StructureSection load='1npo' size='340' side='right' caption='Neurophysin-2 complex with oxytocin (PDB code 1npo)' scene=''> '''Neurophysins''' are carrier proteins which transport h... |
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<StructureSection load='' size='350' side='right' caption='Neurophysin-2 (green and cyan) complex with oxytocin (magenta and salmon) (PDB code [[1npo]])' scene='70/706270/Cv/1' pspeed='8'> | |||
== Function == | |||
'''Neurophysins''' are carrier proteins which transport hormones from the hypothalamus to the posterior pituitary gland<ref>PMID:3147712</ref>. | |||
*'''Neurophysin-1''' transports oxytocin.<br /> | |||
''' | *'''Neurophysin-2''' transports vasopressin.<br /> | ||
*'''Oxytocin''' is used to start labor and increase its speed.<br /> | |||
*'''Vasopressin''' functions to retain water in the body and to constrict blood vessels. | |||
== Disease == | == Disease == | ||
Mutations in neurophysin-2 are associated with familial diabetes<ref>PMID:7714110</ref>. | |||
== Structural highlights == | == Structural highlights == | ||
<scene name='70/706270/Cv/4'>Neurophysin-2/oxytocin interactions</scene>. | |||
</StructureSection> | </StructureSection> | ||
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== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] |