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| <StructureSection load='2z4v' size='350' side='right' scene='' caption='Geranylgeranyl pyrophosphate synthase dimer complex with GGPP and Mg+2 (green) [[2z4v]]'> | | <StructureSection load='' size='350' side='right' scene='54/540181/Cv/1' caption='Geranylgeranyl pyrophosphate synthase dimer complex with GGPP and Mg+2 (green) [[2z4v]]'> |
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| == Function == | | == Function == |
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| == Structural highlights == | | == Structural highlights == |
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| GGPP - the product of GGPPS catalysis interacts with Mg+2 ions in the active site<ref>PMID:18800762</ref>. | | <scene name='54/540181/Cv/5'>GGPP - the product of GGPPS catalysis interacts with Mg+2 ions in the active site</scene><ref>PMID:18800762</ref>. Water molecules shown as red spheres. |
| </StructureSection>
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| == 3D Structures of geranylgeranyl pyrophosphate synthase== | | == 3D Structures of geranylgeranyl pyrophosphate synthase== |
| | [[Geranylgeranyl pyrophosphate synthase 3D structures]] |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | </StructureSection> |
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| [[2dh4]] – yGGPPS + Mg - yeast<br />
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| [[2e8t]] – yGGPPS + Mg + isopentenyl pyrophosphate + farnesyl thiopyrophosphate<br />
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| [[2e8u]], [[2e8w]] – yGGPPS + Mg + isopentenyl pyrophosphate <br />
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| [[2e8v]] – yGGPPS + GGPP<br />
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| [[2z4v]] – yGGPPS + GGPP + Mg<br />
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| [[2e8x]] – yGGPPS + GPP + Mg<br />
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| [[2e90]] – yGGPPS + Mg + PP + farnesyl pyrophosphate<br />
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| [[2e91]], [[2e92]], [[2e93]], [[2e94]], [[2e95]], [[2z7h]], [[2z4w]], [[2z4x]], [[2z4y]], [[2z4z]], [[2z50]], [[2z52]], [[2z78]], [[2z7i]], [[2zeu]] – yGGPPS + Mg + inhibitor<br />
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| [[2zev]] – yGGPPS + Mg + isopentenyl pyrophosphate + inhibitor<br />
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| [[2q80]] – GGPPS + GGPP + Mg - human<br />
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| [[2azj]] – SsGGPPS – ''Sulfolobus solfataricus''<br />
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| [[2azk]] – SsGGPPS (mutant)<br />
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| [[3lk5]], [[3lmd]] – CgGGPPS – ''Corynebacterium glutamicum''<br />
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| [[3q2q]] – CgGGPPS + Ca + isoprenyl diphosphate <br />
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| [[3qqv]] – CgGGPPS + Mg + isoprenyl diphosphate <br />
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| [[3n3d]], [[3pko]] – GGPPS – ''Lactobacillus brevis''<br />
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| [[2j1o]] – SaGGPPS – ''Sinapis alba''<br />
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| [[2j1p]] – SaGGPPS + GGPP<br />
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| == References == | | == References == |
| <references/> | | <references/> |
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| [[Category:Topic Page]] | | [[Category:Topic Page]] |