Bungarotoxin: Difference between revisions

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<StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/2' caption='α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code [[1hc9]])'>
<StructureSection load='1hc9' size='450' side='right' scene='42/423360/Cv/5' caption='α-Bungarotoxin (green) complex with peptide derived from acetylcholine receptor (yellow) and I- ion (PDB code [[1hc9]])'>
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT),  β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br />
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT),  β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br />
*  '''α-BGT'''  binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br />
*  '''α-BGT'''  binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br />
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For toxins in Proteopedia see [[Toxins]].
For toxins in Proteopedia see [[Toxins]].


<scene name='42/423360/Cv/4'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref> Water molecules shown as red spheres.
<scene name='42/423360/Cv/4'>Iod coordination site</scene> in α-Bungarotoxin (PDB code [[1hc9]]).<ref>PMID:11683996</ref> Water molecule shown as red sphere.
</StructureSection>
 
== 3D Structures of Bungarotoxin ==  
== 3D Structures of Bungarotoxin ==  
 
[[Bungarotoxin 3D structures]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


* Bungarotoxin
</StructureSection>
 
**[[2abx]] – α-BGT <br />
**[[1kfh]], [[1ik8]], [[1ikc]], [[1idi]], [[1idl]], [[2nbt]] – α−BGT – NMR<br />
**[[1bun]] - β2-BGT<br />
**[[1mr6]] – γ-BGT – NMR<br />
**[[1kba]] – κ-BGT<br />
 
* BGT+binding peptide
 
**[[1l4w]], [[1ljz]], [[1kc4]], [[1kl8]], [[1jbd]], [[1haa]], [[1haj]], [[1idg]], [[1idh]], [[1hoy]], [[1bxp]], [[1abt]], [[1rgj]], [[2btx]] – α-BGT+AChR peptide - NMR<br />
**[[1hc9]] - α-BGT+AChR peptide<br />
 
* BGT+ AChR subunit


**[[2qc1]] – α-BGT+mAChR α subunit <br />
**[[5hbt]] - α-BGT+ hAChR α1 subunit + antibody<br />
**[[5hbv]] - α-BGT+ mAChR α1 subunit + antibody<br />
**[[4hqp]] - α−BGT+ hAChR α7 subunit<br />
**[[4uy2]] - α−BGT+ hAChR α9 subunit<br />
}}
== References ==
== References ==
<references/>
<references/>

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky, Michal Harel