Barstar: Difference between revisions

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[[Image:2hxx.png|left|200px|thumb|Crystal Structure of Barstar [[2hxx]]]]
<StructureSection load='1a19' size='450' side='right' scene='44/442747/Cv/2' caption='Barstar dimer [[1a19]]'>
{{STRUCTURE_1a19|  PDB=1a19 | SIZE=400| SCENE=|right|CAPTION=Barstar dimer [[1a19]] }}
'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''.  It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.<ref>PMID:8043575</ref>
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''.  It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.
 
__NOTOC__
 
 
 
 
 


== 3D Structures of Barstar ==
== 3D Structures of Barstar ==
[[Barstar 3D structures]]


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
</StructureSection>
 
[[2hxx]], [[2cx6]] – BST<br />
[[1a19]] – BST (mutant)<br />
[[1l1k]], [[1bta]], [[1btb]] – BST – NMR<br />
[[1ab7]] - BST (mutant) - NMR
 
===BST + BA===
 
[[3da7]] – BST + BA (mutant) <br />
[[2za4]], [[1brs]], [[1bgs]] – BST + BA <br />
[[1x1u]], [[1x1w]], [[1x1x]], [[1x1y]], [[1b27]], [[1b2u]] –  BST (mutant) + BA<br />
[[1b3s]], [[1b2s]] - BST (mutant) + BA (mutant)<br />
[[1ay7]] – BST + guanyl-specific RNase SA – ''Streptomyces aureofaciens''


== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 12:26, 31 March 2019

Barstar (BST) is an inhibitor synthesized and secreted by the bacterium Bacillus amyloliquefaciens. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.[1]

3D Structures of Barstar

Barstar 3D structures


Barstar dimer 1a19

Drag the structure with the mouse to rotate

ReferencesReferences

  1. ↑ Buckle AM, Schreiber G, Fersht AR. Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry. 1994 Aug 2;33(30):8878-89. PMID:8043575

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Michal Harel, Alexander Berchansky
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