Formyl-CoA transferase: Difference between revisions

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<StructureSection load='2vjo' size='450' side='right' caption='Structure of formyl-CoA transferase complex with oxalate, CoA, HEPES buffer and Cl- ion (green) (PDB code [[2vjo]]).' scene='59/593959/Cv/1'>
<StructureSection load='' size='350' side='right' caption='Structure of formyl-CoA transferase complex with oxalate, CoA, HEPES buffer and Cl- ion (green) (PDB code [[2vjo]]).' scene='59/593959/Cv/1'>
== Function ==
== Function ==


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== Structural highlights ==
== Structural highlights ==


FCT structure shows <scene name='59/593959/Cv/2'>2 domains: large and small</scene>.  The large domain is composed of residues from the N-terminal and the C-terminal.  The active site binds CoA and oxalate <ref>PMID:18162462</ref>.   
FCT structure shows <scene name='59/593959/Cv/2'>2 domains: large and small</scene>.  The large domain is composed of residues from the N-terminal and the C-terminal.  The active site binds <scene name='59/593959/Cv/10'>oxalate</scene>, <scene name='59/593959/Cv/11'>Cl</scene> and <scene name='59/593959/Cv/12'>CoA</scene> <ref>PMID:18162462</ref>. Water molecules are shown as red spheres.   
 
</StructureSection>
==3D structures of formyl-CoA transferase==
==3D structures of formyl-CoA transferase==


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Michal Harel, Alexander Berchansky, Joel L. Sussman