6f00: Difference between revisions
New page: '''Unreleased structure''' The entry 6f00 is ON HOLD Authors: Charles, B.N., Djemel, H. Description: Crystal Structure of human tRNA-dihydrouridine(20) synthase dsRBD E423A mutant [[Ca... |
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==Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant== | |||
<StructureSection load='6f00' size='340' side='right' caption='[[6f00]], [[Resolution|resolution]] 2.16Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6f00]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F00 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f00 OCA], [http://pdbe.org/6f00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f00 RCSB], [http://www.ebi.ac.uk/pdbsum/6f00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f00 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DUS2L_HUMAN DUS2L_HUMAN]] Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<ref>PMID:15994936</ref> <ref>PMID:18096616</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Charles, B N]] | |||
[[Category: Djemel, H]] | [[Category: Djemel, H]] | ||
[[Category: | [[Category: Double-stranded rna binding domain]] | ||
[[Category: Rna binding protein]] | |||