6fu2: Difference between revisions

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-'''Unreleased structure'''
-The entry 6fu2 is ON HOLD  until Paper Publication
+==ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRPP and ATP==
+<StructureSection load='6fu2' size='340' side='right' caption='[[6fu2]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
-Authors: Alphey, M.S., Ge, Y., Fisher, G., Czekster, C.M., Naismith, J.H., da Silva, R.G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6fu2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU2 FirstGlance]. <br>
-Description: ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRPP and ATP
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_phosphoribosyltransferase ATP phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.17 2.4.2.17] </span></td></tr>
-[[Category: Naismith, J.H]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu2 OCA], [http://pdbe.org/6fu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu2 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/HISZ_PSYA2 HISZ_PSYA2]] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125] [[http://www.uniprot.org/uniprot/HIS1_PSYA2 HIS1_PSYA2]] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
+__TOC__
+</StructureSection>
+[[Category: ATP phosphoribosyltransferase]]
+[[Category: Alphey, M S]]
+[[Category: Czekster, C M]]
 [[Category: Fisher, G]]
 [[Category: Ge, Y]]
-[[Category: Alphey, M.S]]
+[[Category: Naismith, J H]]
-[[Category: Da Silva, R.G]]
+[[Category: Silva, R G.da]]
-[[Category: Czekster, C.M]]
+[[Category: Atp phosphoribosyltransferase]]
+[[Category: Cold-adapted]]
+[[Category: Hiszg]]
+[[Category: Transferase]]