6ha5: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ha5 is ON HOLD
+==AFGH61B L90V/D131S/M134L/A141W VARIANT==
+<StructureSection load='6ha5' size='340' side='right' caption='[[6ha5]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ha5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspfu Aspfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HA5 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[61hz|61hz]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AFUA_4G07850 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=330879 ASPFU])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ha5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ha5 OCA], [http://pdbe.org/6ha5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ha5 RCSB], [http://www.ebi.ac.uk/pdbsum/6ha5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ha5 ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Lytic polysaccharide monooxygenases (LPMOs) are industrial enzymes which are gaining use in second generation bioethanol production from lignocellulose by acting in synergy with glycoside hydrolases. Here we present the X-ray crystal structure of an AA9 fungal LPMO from Aspergillus fumigatus and a variant which has been shown to have better performance at elevated temperatures. Based on the structures, thermal denaturation data and theoretical calculations, we provide a suggestion for the structural basis of the improved stability.
-Authors: Lo Leggio, L., Poulsen, J.C.N.
+Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant.,Lo Leggio L, Weihe CD, Poulsen JN, Sweeney M, Rasmussen F, Lin J, De Maria L, Wogulis M Carbohydr Res. 2018 Nov;469:55-59. doi: 10.1016/j.carres.2018.08.009. Epub 2018, Aug 14. PMID:30296642<ref>PMID:30296642</ref>
-Description: AFGH61B L90V/D131S/M134L/A141W VARIANT
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Poulsen, J.C.N]]
+<div class="pdbe-citations 6ha5" style="background-color:#fffaf0;"></div>
-[[Category: Lo Leggio, L]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Aspfu]]
+[[Category: Leggio, L Lo]]
+[[Category: Poulsen, J C.N]]
+[[Category: Lytic polysaccharide monooxygenase]]
+[[Category: Oxidoreductase]]