6ey7: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ey7 is ON HOLD  until Paper Publication
+==Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound==
+<StructureSection load='6ey7' size='340' side='right' caption='[[6ey7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-Authors: Borganzone, S., Nadal, M., Kaczmarska, Z., Machon, M., Alvarez, M., Albericio, F., Coll, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ey7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hcmva Hcmva]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EY7 FirstGlance]. <br>
-Description: Human cytomegalovirus terminase nuclease domain, Mn soaked, inhibitor bound
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C3W:4-[(4-fluorophenyl)methyl-methyl-amino]-2,4-bis(oxidanylidene)butanoic+acid'>C3W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UL89 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10360 HCMVA])</td></tr>
-[[Category: Kaczmarska, Z]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ey7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ey7 OCA], [http://pdbe.org/6ey7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ey7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ey7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ey7 ProSAT]</span></td></tr>
-[[Category: Borganzone, S]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA]] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Hcmva]]
 [[Category: Albericio, F]]
 [[Category: Alvarez, M]]
-[[Category: Machon, M]]
+[[Category: Bongarzone, S]]
+[[Category: Coll, M]]
+[[Category: Kaczmarska, Z]]
+[[Category: Machon, C]]
 [[Category: Nadal, M]]
-[[Category: Coll, M]]
+[[Category: Cytomegalovirus]]
+[[Category: Drug design]]
+[[Category: Inhibitor]]
+[[Category: Raltegravir]]
+[[Category: Terminase]]
+[[Category: Ul89]]
+[[Category: Viral protein]]