Fasciculin: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman

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-[[Image:1fas.png|left|200px|thumb|Crystal Structure of Fasciculin [[1fas]]]]
+<StructureSection load='' size='350' side='right' caption='Structure of Fasciculin 1 (PDB entry [[1fas]])' scene='Fasciculin/Cv/1'>
-{{STRUCTURE_1fas|  PDB=1fas  | SIZE=300| SCENE=Fasciculin/Cv/1 |right|CAPTION=Fasciculin [[1fas]] }}
-[[Fasciculin|Fasciculins]] (FASs) are toxins produced by the snake green mamba.  FASI and FASII are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE)  and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, ''i.e.'' the crystal structure of Fasciculin 1 ([[1fas]]).  For toxins in Proteopedia see [[Toxins]].
+[[Fasciculin|Fasciculins]] (FAS) are toxins produced by the snake green mamba.  FAS1 and FAS2 are known to bind to [[acetylcholinesterase|acetylcholinesterase]] (AChE)  and cause severe fasciculations<ref>PMID:6530667</ref> .  For toxins in Proteopedia see [[Toxins]].
 {{TOC limit|limit=2}}
+</StructureSection>
 == 3D Structures of Fasciculin ==
-''Update January 2013''
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+{{#tree:id=OrganizedByTopic|openlevels=0|
-=== Fasciculin ===
-[[1fas]] – FASI <br />
-[[1fsc]] - FASII<br />
+* Fasciculin
-=== FAS+ AChE ===
+**[[1fas]] – FAS1 <br />
+**[[1fsc]] - FAS2<br />
+* FAS+ AChE
-[[2x8b]], [[1b41]], [[4ey8]] – FASII+hAChE – human<br />
+**[[2x8b]], [[1b41]], [[4ey8]], [[4bdt]] – FAS2+hAChE – human<br />
-[[1f8u]] - FASII+hAChE (mutant)<br />
+**[[1f8u]] - FAS2+hAChE (mutant)<br />
-[[1ku6]], [[1mah]] - FASII+mAChE – mouse<br />
+**[[1ku6]], [[1mah]] - FAS2+mAChE – mouse<br />
-[[1fss]] - FASII+AChE – ''Torpedo californica''<br />
+**[[1fss]] - FAS2+AChE – ''Torpedo californica''<br />
+}}
+== References ==
+<references/>
 [[Category:Topic Page]]