Isopropylmalate isomerase: Difference between revisions

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New page: <StructureSection load='5h5e' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Isopropylmalate isomerase''' (IPMI) catalyzes a stereo-specific is...
 
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<StructureSection load='1v7l' size='340' side='right' caption='3-isopropylmalate isomerase small subunit (PDB code [[1v7l]])' scene=''>  
<StructureSection load='5h5e' size='340' side='right' caption='Caption for this structure' scene=''>  


== Function ==
== Function ==
'''Isopropylmalate isomerase''' (IPMI) catalyzes a stereo-specific isomerization of 3-isopropylmalate by dehydration followed by rehydration at a different position to 2-isopropylmalate.  IPMI contains an Fe4S4 center.  IPMI is a homodimer composed of a large subunit (LeuC) and a small subunit (LeuD)<ref>PMID:15522288</ref>.
'''Isopropylmalate isomerase''' (IPMI) catalyzes a stereo-specific isomerization of 3-isopropylmalate by dehydration followed by rehydration at a different position to 2-isopropylmalate.  IPMI is a homodimer composed of a large subunit (LeuC) and a small subunit (LeuD)<ref>PMID:15522288</ref>.
 
== Disease ==
 
== Relevance ==
 
== Structural highlights ==
 


</StructureSection>
</StructureSection>
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[[2hcu]] – SmIPMI small subunit – ''Streptococcus mutans''<br / >
[[2hcu]] – SmIPMI small subunit – ''Streptococcus mutans''<br / >
[[3q3w]] – CjIPMI small subunit – ''Campylobacter jejuni''<br / >
[[3q3w]] – CjIPMI small subunit – ''Campylobacter jejuni''<br / >
[[3vba]] – MjIPMI small subunit – ''Methanocaldococcus janaschii''<br / >
[[3vba]], [[2pkp]] – MjIPMI small subunit – ''Methanocaldococcus janaschii''<br / >
[[4kp1]], [[4nqy]] – MjIPMI large subunit <br / >
[[4kp1]], [[4nqy]] – MjIPMI large subunit <br / >
[[3h5e]], [[5h5h]], [[5h5j]] – MtIPMI small subunit – ''Mycobacterium tuberculosis''<br / >
[[3h5e]], [[3h5h]], [[3h5j]] – MtIPMI small subunit – ''Mycobacterium tuberculosis''<br / >


== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]

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Michal Harel