Eglin: Difference between revisions

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[[Image:1egp.png|left|200px|thumb|Crystal Structure of Leech Eglin, [[1egp]]]]
{{STRUCTURE_1egp|  PDB=1egp  | SIZE=300| SCENE=Eglin/Cv/1 |right|CAPTION=Cleaved leech Eglin, [[1egp]] }}


[[Eglin]] C is a serine proteinase inhibitor isolated from leech. The images at the left and at the right correspond to one representative Eglin structure, ''i.e.'' crystal structure of Leech Eglin ([[1egp]]) which was cleaved between residues 45 and 46.
<StructureSection load='1egp' size='350' side='right' caption='Cleaved leech Eglin.  Residues 1-45 (grey) and 46-70 (green) (PDB code [[1egp]]).' scene='Eglin/Cv/1'>


{{TOC limit|limit=2}}
'''Eglin C''' is a serine proteinase inhibitor isolated from leech. <ref>PMID:3064813</ref>


== Relevance ==
Eglin C and its mutants are tested as protease inhibitor drugs.
</StructureSection>
== 3D Structures of Eglin ==
== 3D Structures of Eglin ==


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[[4h4f]] - lEglin-C+ hChymotrypsin – human<br />
[[4h4f]] - lEglin-C+ hChymotrypsin – human<br />


== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

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Alexander Berchansky, Michal Harel, Jaime Prilusky