Eglin: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky

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-[[Image:1egp.png|left|200px|thumb|Crystal Structure of Leech Eglin, [[1egp]]]]
-{{STRUCTURE_1egp|  PDB=1egp  | SIZE=300| SCENE= |right|CAPTION=Leech Eglin, [[1egp]] }}
-[[Eglin]] C is a serine proteinase inhibitor isolated from leech. The images at the left and at the right correspond to one representative Eglin structure, ''i.e.'' crystal structure of Leech Eglin ([[1egp]]) which was cleaved between residues 45 and 46.
+<StructureSection load='1egp' size='350' side='right' caption='Cleaved leech Eglin.  Residues 1-45 (grey) and 46-70 (green) (PDB code [[1egp]]).' scene='Eglin/Cv/1'>
-{{TOC limit|limit=2}}
+'''Eglin C''' is a serine proteinase inhibitor isolated from leech. <ref>PMID:3064813</ref>
+== Relevance ==
+Eglin C and its mutants are tested as protease inhibitor drugs.
+</StructureSection>
 == 3D Structures of Eglin ==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 [[1egp]] – lEglin-C – leech<br />
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 [[1sbn]], [[1sib]], [[1cse]] - lEglin-C+BsSubtilisin – ''Bacillus subtilis''<br />
 [[2sec]] - lEglin-C+BlSubtilisin – ''Bacillus licheniformis''<br />
-[[1acb]] - lEglin-C+cChymotrypsinogen – cow<br />
+[[1acb]] - lEglin-C+bChymotrypsinogen – bovine<br />
+[[4b1t]], [[4b2a]], [[4b2b]], [[4b2c]] - lEglin-C (mutant) +bTrypsin (mutant) <br />
 [[1mee]] - lEglin-C+BpMesentericopeptidase – ''Bacillus pumilus''<br />
 [[2tec]], [[3tec]], [[1tec]] - lEglin-C+TvThermitase – ''Thermoactinomyces vulgaris''<br />
+[[4h4f]] - lEglin-C+ hChymotrypsin – human<br />
+== References ==
+<references/>
 [[Category:Topic Page]]