4pqe: Difference between revisions
No edit summary |
No edit summary |
||
(4 intermediate revisions by one other user not shown) | |||
Line 1: | Line 1: | ||
''' | ==Crystal Structure of Human Acetylcholinesterase== | ||
<StructureSection load='4pqe_au' size='340' side='right' caption='[[4pqe]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4pqe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PQE FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lii|3lii]], [[4ey4|4ey4]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pqe OCA], [http://pdbe.org/4pqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pqe RCSB], [http://www.ebi.ac.uk/pdbsum/4pqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pqe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref> | |||
==See Also== | |||
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Acetylcholinesterase]] | |||
[[Category: Dym, O]] | |||
[[Category: ISPC, Israel Structural Proteomics Center]] | |||
[[Category: Silman, I]] | |||
[[Category: Sussman, J L]] | |||
[[Category: Toker, L]] | |||
[[Category: Unger, T]] | |||
[[Category: Alpha/beta hydrolase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Structural genomic]] |