2dkg: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2dkg.gif|left|200px]]<br /><applet load="2dkg" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="2dkg, resolution 2.00&Aring;" />
-'''Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotinyl-5'-AMP, Pyrophosphate and Mg(2+)'''<br />
-==About this Structure==
+==Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotinyl-5'-AMP, Pyrophosphate and Mg(2+)==
-DKG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=BT5:'>BT5</scene> and <scene name='pdbligand=POP:'>POP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKG OCA].
+<StructureSection load='2dkg' size='340' side='right' caption='[[2dkg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-[[Category: Biotin--[acetyl-CoA-carboxylase] ligase]]
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2dkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKG FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BT5:BIOTINYL-5-AMP'>BT5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wgw|1wgw]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">birA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkg OCA], [http://pdbe.org/2dkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dkg RCSB], [http://www.ebi.ac.uk/pdbsum/2dkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkg ProSAT], [http://www.topsan.org/Proteins/RSGI/2dkg TOPSAN]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dkg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dkg ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Biotin Protein Ligase|Biotin Protein Ligase]]
+__TOC__
+</StructureSection>
 [[Category: Pyrococcus horikoshii]]
-[[Category: Single protein]]
+[[Category: Bagautdinov, B]]
-[[Category: Bagautdinov, B.]]
+[[Category: Kunishima, N]]
-[[Category: Kunishima, N.]]
+[[Category: Structural genomic]]
-[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+[[Category: Biotin biosynthesis]]
-[[Category: BT5]]
+[[Category: Dimer]]
-[[Category: MG]]
+[[Category: Ligase]]
-[[Category: POP]]
+[[Category: National project on protein structural and functional analyse]]
-[[Category: biotin biosynthesis]]
+[[Category: Nppsfa]]
-[[Category: dimer]]
+[[Category: Rsgi]]
-[[Category: national project on protein structural and functional analyses]]
-[[Category: nppsfa]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomics]]
-[[Category: x-ray diffraction]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 19:04:40 2008''