4qrd: Difference between revisions

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'''Unreleased structure'''
==Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine==
 
<StructureSection load='4qrd' size='340' side='right' caption='[[4qrd]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
The entry 4qrd is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4qrd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QRD FirstGlance]. <br>
Authors: Li, X., Hilgers, M. T., Stidham, M., Brown-Driver, V., Shaw, K. J., Finn, J.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3BJ:N-(1H-BENZIMIDAZOL-2-YLMETHYL)-N-(2,4-DICHLOROPHENYL)-6-(MORPHOLIN-4-YL)-1,3,5-TRIAZINE-2,4-DIAMINE'>3BJ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qre|4qre]]</td></tr>
Description: Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synthetase
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qrd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qrd RCSB], [http://www.ebi.ac.uk/pdbsum/4qrd PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Methionine--tRNA ligase]]
[[Category: Brown-Driver, V]]
[[Category: Finn, J]]
[[Category: Hilgers, M T]]
[[Category: Li, X]]
[[Category: Shaw, K J]]
[[Category: Stidham, M]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Aminoacylation]]
[[Category: Cytosol]]
[[Category: Ligase-ligase inhibitor complex]]
[[Category: Protein synthesis]]

Latest revision as of 17:46, 29 July 2015

Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamineStructure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine

Structural highlights

4qrd is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Methionine--tRNA ligase, with EC number 6.1.1.10
Resources:FirstGlance, OCA, RCSB, PDBsum

4qrd, resolution 1.97Å

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