FhuD: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Andrea Gorrell, Leni Rose, William Eisbrenner, David Canner, Michal Harel, Alexander Berchansky

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 =='''PERIPLASMIC FERRIC SIDEROPHORE BINDING PROTEIN FHUD COMPLEXED WITH ALBOMYCIN (1esz)'''==
-<applet load='1esz' size='400' frame='true' align='right' caption='Strucutre of the Periplasmic Ferric Siderophore Binding Protein FhuD complexed with Albomycin as determined by Clarke et al.' />
+<applet load='1esz' size='400' frame='true' align='right' caption='Strucutre of the Periplasmic Ferric Siderophore Binding Protein FhuD complexed with the siderophore coprogen as determined by Clarke et al. [[1esz]]' />
 ==OVERVIEW==
-Siderophore-binding proteins can be found in both Gram-positive and Gram-negative bacteria in divisions: hydroxamates, catecholates, and carboxylates.<ref name="lu">PMID: 11805094</ref>  In Escherichia coli. (E. coli) the ATP-binding cassette- type (ABC-type) protein FhuD (part of the helical backbone metal receptor superfamily) is a common periplasmic protein which facilitates the transport of a variety of hydoxamate siderophores to the inner membrane-associated proteins FhuB and FhuC.<ref name="lu"/> The structure of FhuD is atypical for periplasmic ligand binding protein due to its bilobal mixture of two α/β domains connected by long α-helix.<ref name="lu"/>,<ref name="la">PMID: 10742172</ref>
+Siderophore-binding proteins can be found in both Gram-positive and Gram-negative bacteria in divisions: hydroxamates, catecholates, and carboxylates.<ref name="lu">PMID: 11805094</ref>  In Escherichia coli. (E. coli) the ATP-binding cassette- type (ABC-type) protein '''FhuD''' (part of the helical backbone metal receptor superfamily) is a common periplasmic protein which facilitates the transport of a variety of hydoxamate siderophores to the inner membrane-associated proteins FhuB and FhuC.<ref name="lu"/> The structure of FhuD is atypical for periplasmic ligand binding protein due to its bilobal mixture of two α/β domains connected by long α-helix.<ref name="lu"/>,<ref name="la">PMID: 10742172</ref>
 ==PROTEIN STRUCTURE==
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 ==3D structures of FhuD==
-[[3hxp]] – BsFhuD – ''Bacillus subtilis''<br />
+[[Ferric hydroxamate uptake receptor]].
-[[3g9q]] – BsFhuD residues 45-315<br />
-[[1esz]] – EcFhuD + coprogen – ''Escherichia coli''<br />
-[[1k2v]] – EcFhuD + desferal<br / >
-[[1k7s]] – EcFhuD + albomycin-δ 2<br />
-[[1efd]] – EcFhuD + gallichrome
 ==REFERENCES==
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 [[User:Leni Rose|Leni Rose]] 04:57, 13 March 2010 (IST)
+[[Category:Topic Page]]