OmpF: Difference between revisions

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{{STRUCTURE_3o0e |  PDB=3o0e  | SCENE= OmpF/Ompfcole9mono/1 }}
{{STRUCTURE_3o0e|  PDB=3o0e  | SIZE=400| SCENE= |right|CAPTION=OmpF complex with colicin peptide and beta-octylglucoside, [[3o0e]] }}


OmpF is a major outer membrane porin found in ''E. coli''. Mutations in the ''ompF'' gene result in a reduced sensitivity of the ''E. coli'' cell to proteins such as [[Colicin]]s, and also bacteriophages<ref> PMID: 3543211 </ref>.
 
 
'''OmpF''' is a major outer membrane porin found in ''E. coli''. Mutations in the ''ompF'' gene result in a reduced sensitivity of the ''E. coli'' cell to proteins such as [[Colicin]]s, and also bacteriophages<ref> PMID: 3543211 </ref>.


OmpF production is regulated by OmpR, a protein that is phosphorylated by EnvZ to induce DNA binding to the promotor region of OmpF, and repress transcription of OmpF<ref> PMID: 2668953 </ref><ref> PMID: 2656631 </ref>.
OmpF production is regulated by OmpR, a protein that is phosphorylated by EnvZ to induce DNA binding to the promotor region of OmpF, and repress transcription of OmpF<ref> PMID: 2668953 </ref><ref> PMID: 2656631 </ref>.


This structure shows a monomer of <scene name='OmpF/Ompfmono/1'>OmpF</scene>, bound to a <scene name='OmpF/Synthcole9/1'>synthetic construct</scene> of a region of the translocation domain of [[Colicin E9]].
This structure shows a monomer of <scene name='OmpF/Ompfmono/1'>OmpF</scene>, bound to a <scene name='OmpF/Synthcole9/1'>synthetic construct</scene> of a region of the translocation domain of [[Colicin E9]].
==3D structures of porin==
[[Porin]]


==References==
==References==


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Gemma McGoldrick, Michal Harel