User:Nicholas P. Taliceo/Sandbox: Difference between revisions
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<scene name='60/609967/Ibuprofen_single_molecule/5'>Ibuprofen Single Molecule</scene> | <scene name='60/609967/Ibuprofen_single_molecule/5'>Ibuprofen Single Molecule</scene> | ||
< | *<jmol> | ||
<jmolLink> | |||
< | <script> select 701:A; color CPK; spacefill 23%; var a = [300,250,200,170,140,120,100]; for(var i IN a) {wireframe @i; delay 0.4;} | ||
</script> | |||
<text>Show the atoms </text> | |||
</jmolLink> | |||
</jmol> | |||
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<scene name='60/609967/Allatom/4'>Protein buries ligands</scene> | <scene name='60/609967/Allatom/4'>Protein buries ligands</scene> | ||
<jmol> | *<jmol> | ||
<jmolLink> | <jmolLink> | ||
<script> slab on; depth 40; var a = [90,80,70,60,55,54,53,52,51]; for(var i IN a) {slab @i; delay 0.4;} | <script> slab on; depth 40; var a = [90,80,70,60,55,54,53,52,51]; for(var i IN a) {slab @i; delay 0.4;} | ||
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</jmol> | </jmol> | ||
<jmol> | *<jmol> | ||
<jmolLink> | <jmolLink> | ||
<script> slab on; depth 40; var a = [51,52,53,54,55,60,70,80,90,100]; for(var i IN a) {slab @i; delay 0.4;} | <script> slab on; depth 40; var a = [51,52,53,54,55,60,70,80,90,100]; for(var i IN a) {slab @i; delay 0.4;} | ||
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</StructureSection> | </StructureSection> | ||
== Function == | == Function == | ||
The protein sits on the surface of a membrane, and makes prostaglandin hormones when not inhibited. There is a nice [ | The protein sits on the surface of a membrane, and makes prostaglandin hormones when not inhibited. There is a nice [http://www.rcsb.org/pdb/education_discussion/molecule_of_the_month/images/4cox_tunnel.gif figure] of the protein and the membrane in a molecule of the month article by David Goodsell. | ||
<scene name='60/609967/With_membrane/1'>Membrane orientation</scene> | |||
Latest revision as of 01:29, 24 December 2014
Structure of the Ibuprofen Molecule
Ibuprofen binds to the protein cyclooxygenase
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FunctionFunction
The protein sits on the surface of a membrane, and makes prostaglandin hormones when not inhibited. There is a nice figure of the protein and the membrane in a molecule of the month article by David Goodsell.