|
|
| (22 intermediate revisions by 3 users not shown) |
| Line 1: |
Line 1: |
| <applet load="1dk0" size="300" frame="true" align="right" /> | | <Structure load='1dzy' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><!-- |
| The Hasa hemophore from <i>Serratia Marcescens</i> is a most unique and sinister protein thqt grabs away the heme and its iron from the homoglobin of those unfortunate humans and animals that happen to become infected by this bug. Indeed, the ConSurf web site at consurf.tau.ac.il has shown that this protein's sequence is close to being unique in the sequence database. For more information please see page [[1dk0]].
| | Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page. |
| <p>One of the major problems that micro-organisms have is to extract iron in its ferric and ferrous ionic forms from the scarce environment. While many
| | Or use the four-green-boxes-button to insert scrollable text adjacent |
| creatures that live in soil, lakes and other natural settings utilize small organic carrier molecules called siderophores; dangerous disease organisms that infect humans and animals take advantage of the iron stored in the infected host, whose iron is mainly in heme groups (hemoglobin) and iron-sulfer complexes. Hasa is an example of a protein called a hemophore that seizes away the hemes including their iron from hemoglobin and myoglobin, by complexing and heme with significantly much greater affinity (eg. binds it much more tightly).
| | to a Jmol applet. Check out the other buttons as well! |
| | --> |
| | |
| | <scene name='Sandbox_17/Temperature/1'>Temperature</scene> |