C-di-GMP: Difference between revisions
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Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid) | <applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP, as found in complex with the diguanylate cyclase PleD [[2v0n]]' /> | ||
Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)<br><br> | |||
C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | ||
<scene name=' | <scene name='C-di-GMP/C-di-gmp/3'>C-di-GMP</scene> | ||
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form <scene name='C-di-GMP/C-di-gmp/ | is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form <scene name='C-di-GMP/C-di-gmp/4'>dimers</scene> with intercalated, stacked bases. | ||
Several protein structures involved in c-di-GMP signaling have been determined ( | Several protein structures involved in c-di-GMP signaling have been determined (see [[C-di-GMP signaling]]). | ||
<br><br><br><br><br><br><br><br><br><br> | <br><br> | ||
[http://www.uniprot.org/keywords/973 UNIPROT link] | |||
<br><br><br><br><br><br><br><br> | |||
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==References== | ==References== | ||
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<ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref> | <ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref> | ||
<references group="xtra"/> | <references group="xtra"/> | ||
[[Category: C-di-GMP]] | |||
Latest revision as of 23:45, 8 January 2012
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Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)
C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.
Several protein structures involved in c-di-GMP signaling have been determined (see C-di-GMP signaling).
ReferencesReferences
- ↑ Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3235-9. PMID:2158107
- ↑ Guan Y, Gao YG, Liaw YC, Robinson H, Wang AH. Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies. J Biomol Struct Dyn. 1993 Oct;11(2):253-76. PMID:8286055