YbgC: Difference between revisions
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{{STRUCTURE_2pzh | PDB=2pzh | SCENE= }} | {{STRUCTURE_2pzh | PDB=2pzh | SCENE= }} | ||
YbgCis believed to have first appeared in the [[Tol]] complex with the separation of the δε proteobacteria from the αβγ proteobacteria<ref name='Sturgis'>PMID: 11200223</ref>. | |||
== | ==Structure== | ||
YbgC is a cytoplasmic protein in the Tol-[[Pal]] complex<ref>PMID: 11994151</ref>. In ''Helicobacter pylori'', the protein is part of a 'hot-dog' family of proteins, with an epsilongamma tetrameric arrangement<ref name='Angelini'>PMID: 18338382</ref>. | |||
==Function== | |||
The protein displays thioesterase activity towards acyl-CoA thioesters<ref name='Angelini'>PMID: 18338382</ref>, and has a strong sequence conservation with its active site residues with other proteins of a similar function<ref>PMID: 9837940</ref> for example with the ''Pseudonomas'' sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase<ref>PMID: 11959124</ref>. | |||
However, its role within the Tol complex itself remains unknown, although it may be involved in the acetylation of another protein within the complex, with the role of an activity-regulator<ref name='Sturgis'>PMID: 11200223</ref>. It is also thought to be involved in the cell division complex of Tol-Pal<ref name='Angelini'>PMID: 18338382</ref>. | |||
== References== | == References== | ||
<references/> | <references/> | ||